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1. (WO2005010007) SUBSTITUTED FUROCHROMENES, PREPARATION THEREOF AND THEIR ANTIINFLAMMATORY ACTION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/010007 International Application No.: PCT/HR2004/000021
Publication Date: 03.02.2005 International Filing Date: 22.07.2004
IPC:
C07D 493/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
493
Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants:
MERCEP, Mladen [HR/HR]; HR (UsOnly)
MESIC, Milan [HR/HR]; HR (UsOnly)
HRVACIC, Boska [HR/HR]; HR (UsOnly)
ELENKOV, Ivaylo Jivkov [HR/HR]; HR (UsOnly)
MALNAR, Ivica [HR/HR]; HR (UsOnly)
MARKOVIC, Stribor [HR/HR]; HR (UsOnly)
SIMICIC, Lidija [HR/HR]; HR (UsOnly)
CEMPUH KLONKAY, Andreja [HR/HR]; HR (UsOnly)
FILIPOVIC, Anita [HR/HR]; HR (UsOnly)
PLIVA- ISTRAZIVACKI INSTITUT D.O.O. [HR/HR]; Prilaz baruna Filipovica 29 10 000 Zagreb, HR (AllExceptUS)
Inventors:
MERCEP, Mladen; HR
MESIC, Milan; HR
HRVACIC, Boska; HR
ELENKOV, Ivaylo Jivkov; HR
MALNAR, Ivica; HR
MARKOVIC, Stribor; HR
SIMICIC, Lidija; HR
CEMPUH KLONKAY, Andreja; HR
FILIPOVIC, Anita; HR
Common
Representative:
PLIVA- ISTRAZIVACKI INSTITUT D.O.O.; Prilaz baruna Filipovica 29 10 000 Zagreb, HR
Priority Data:
P20030604A25.07.2003HR
Title (EN) SUBSTITUTED FUROCHROMENES, PREPARATION THEREOF AND THEIR ANTIINFLAMMATORY ACTION
(FR) FUROCHROMENES SUBSTITUES, PREPARATION DE CEUX-CI ET LEUR ACTION ANTI-INFLAMMATOIRE
Abstract:
(EN) The invention relates to novel compounds of formula (I) including all their tautomers to pharmaceutically acceptable salts and solvates thereof, to processes and reactive intermediates for the preparation thereof; to processes and reactive intermediates for the preparation of compounds of formula (II) including all their stereoisomers and tautomers to the use of the compounds of the formula (II) as suitable precursors for the preparation of the compounds of the formula (I) as well as to use of the compounds of the formula (I) and of the compounds of the formula (II) as therapeutically active agents in the prophylaxis and treatment of asthma and other inflammatory diesases and conditions in humans.
(FR) L'invention concerne de nouveaux composés de formule (I), y compris tous leurs tautomères. L'invention concerne également des sels pharmaceutiquement acceptables et des solvates de ceux-ci. L'invention concerne des procédés et des intermédiaires réactifs pour la préparation de ceux-ci. L'invention concerne des procédés et des intermédiaires réactifs pour la préparation de composés de formule (II), y compris tous leurs stéréisomères et leurs tautomères. L'invention concerne l'utilisation des composés de formule (II) en tant que précurseurs appropriés à la préparation des composés de formule (I), ainsi que l'utilisation des composés de formule (I) et des composés de formule (II) en tant qu'agents thérapeutiquement actifs pour la prophylaxie et pour le traitement de l'asthme et d'autres maladies inflammatoires, ainsi que de troubles chez les humains.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)