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1. (WO2005009951) DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/009951 International Application No.: PCT/US2004/023334
Publication Date: 03.02.2005 International Filing Date: 20.07.2004
IPC:
A61K 31/535 (2006.01) ,C07D 221/02 (2006.01) ,C07D 231/02 (2006.01) ,C07D 263/02 (2006.01)
Applicants: CHU, Lin[US/US]; US (UsOnly)
GOULET, Mark, T.[US/US]; US (UsOnly)
UJJAINWALLA, Feroze[GB/US]; US (UsOnly)
FRENETTE, Richard[CA/CA]; CA (UsOnly)
GIRARD, Yves[CA/CA]; CA (UsOnly)
THERIEN, Michel[CA/CA]; CA (UsOnly)
MACDONALD, Dwight[CA/CA]; CA (UsOnly)
HUTCHINSON, John, H.[CA/US]; US (UsOnly)
CHANG, Linda[CA/US]; US (UsOnly)
MERCK & CO., INC.[US/US]; 126 East Lincoln Avenue Rahway, NJ 07065-0907, US (AllExceptUS)
MERCK FROSST CANADA LTD.[CA/CA]; 16711 Trans-Canada Highway Kirkland, Québec H9H 3L1, CA (AllExceptUS)
Inventors: CHU, Lin; US
GOULET, Mark, T.; US
UJJAINWALLA, Feroze; US
FRENETTE, Richard; CA
GIRARD, Yves; CA
THERIEN, Michel; CA
MACDONALD, Dwight; CA
HUTCHINSON, John, H.; US
CHANG, Linda; US
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue Rahway, NJ 07065-0907, US
Priority Data:
60/489,69324.07.2003US
Title (EN) DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE
(FR) CYCLOALCANES DIPHENYL-SUBSTITUTES, COMPOSITIONS CONTENANT CES COMPOSES, ET PROCEDES D'UTILISATION
Abstract:
(EN) The instant invention provides compounds of formula: (I) which are 5-lipoxygenase activating protein inhibitors: formula (I). Compounds of formula (I) are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
(FR) La présente invention concerne des composés de formule (I) qui sont des inhibiteurs de protéine d'activation de 5-lipoxygénase. Les composés de formule (I) sont utiles en tant qu'agents anti-athérosclérotiques, anti-asthmatiques, hypoallergéniques, anti-inflammatoires et cytoprotecteurs.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)