WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Options
Query Language
Stem
Sort by:
List Length
Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2005009347) 7-SUBSTITUTED CAMPTOTHECIN AND CAMPTOTHECIN ANALOGS AND METHODS FOR PREPARING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2005/009347 International Application No.: PCT/US2004/020388
Publication Date: 03.02.2005 International Filing Date: 25.06.2004
IPC:
C07D 491/22 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
491
Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
22
in which the condensed system contains four or more hetero rings
Applicants: WANI, Mansukh, C.[US/US]; US (UsOnly)
MANIKUMAR, Govindarajan[US/US]; US (UsOnly)
WALL, Michael, A.[US/US]; US (UsOnly)
RESEARCH TRIANGLE INSTITUTE[US/US]; P.O. Box 12194 3040 Cornwallis Road Research Triangle Park, NC 27709, US (AllExceptUS)
Inventors: WANI, Mansukh, C.; US
MANIKUMAR, Govindarajan; US
WALL, Michael, A.; US
Agent: MASON, J., Derek; Oblon, Spivak, McClelland, Maier & Neustadt, P.C. 1940 Duke Street Alexandria, VA 22314, US
Priority Data:
10/606,79527.06.2003US
Title (EN) 7-SUBSTITUTED CAMPTOTHECIN AND CAMPTOTHECIN ANALOGS AND METHODS FOR PREPARING SAME
(FR) CAMPTOTHECINE 7-SUBSTITUEE ET ANALOGUES DE CAMPTOTHECINE ET LEURS PROCEDES DE PREPARATION
Abstract:
(EN) Methods of forming camptothecin compounds which are effective anti-tumor compounds are disclosed. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I-DNA cleavable complex.
(FR) L'invention concerne des procédés de formation de composés de camptothécine qui sont des antitumoraux efficaces. Ces composés inhibent l'enzyme topoisomérase I et peuvent alkyler l'ADN du complexe associé clivable de l'ADN de la topoisomérase I.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)