Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2005004809) MULTIVALENT CARRIERS OF BI-SPECIFIC ANTIBODIES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2005/004809 International Application No.: PCT/US2004/020995
Publication Date: 20.01.2005 International Filing Date: 01.07.2004
IPC:
C07K 16/00 (2006.01) ,A61K 39/395 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
Applicants:
IMMUNOMEDICS, INC. [US/US]; 300 American Road Morris Plains, NJ 07950, US (AllExceptUS)
HANSEN, Hans, J. [US/US]; US (UsOnly)
MCBRIDE, William, J. [US/US]; US (UsOnly)
QU, Zhengxing [US/US]; US (UsOnly)
Inventors:
HANSEN, Hans, J.; US
MCBRIDE, William, J.; US
QU, Zhengxing; US
Agent:
BOOTH, Paul, M. ; Heller Ehrman White & McAuliffe LLP Suite 300 1666 K Street, NW Washington, DC 20006-1228, US
Priority Data:
60/483,83201.07.2003US
Title (EN) MULTIVALENT CARRIERS OF BI-SPECIFIC ANTIBODIES
(FR) PORTEUSES POLYVALENTES D'ANTICORPS BISPECIFIQUES
Abstract:
(EN) Provided herein are targetable constructs that are multivalent carriers of bi-specific antibodies, i.e., each molecule of a targetable construct can serve as a carrier of two or more bi-specific antibodies. Also provided are targetable complexes formed by the association of a targetable construct with two or more bi-specific antibodies. The targetable constructs and targetable complexes of the invention are incorporated into biosensors, kits and pharmaceutical compositions, and are used in a variety of therapeutic and other methods.
(FR) L'invention concerne des constructions pouvant être ciblées qui sont des porteuses polyvalentes d'anticorps bispécifiques, c'est-à-dire, que chaque molécule d'une construction pouvant être ciblée peut servir en tant que porteuse d'au moins deux anticorps bispécifiques. L'invention concerne également des complexes pouvant être ciblés formés par l'association d'une construction pouvant être ciblée avec au moins deux anticorps bispécifiques. Les constructions pouvant être ciblées et les complexes pouvant être ciblés de l'invention sont incorporés dans des biodétecteurs, des kits et des compositions pharmaceutiques, et ils sont utilisés dans une pluralité de procédés thérapeutiques et d'autres procédés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)