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1. WO2004111656 - COAGULATION TESTS AT AMBIENT TEMPERATURE

Publication Number WO/2004/111656
Publication Date 23.12.2004
International Application No. PCT/SE2004/000940
International Filing Date 15.06.2004
IPC
G01N 33/49 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
487of liquid biological material
49blood
CPC
G01N 33/4905
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
483Physical analysis of biological material
487of liquid biological material
49Blood
4905Determining clotting time of blood
G01N 33/86
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
86involving blood coagulating time ; or factors, or their receptors
Applicants
  • ZAFENA AB [SE]/[SE] (AllExceptUS)
  • RÅNBY, Mats [SE]/[SE] (UsOnly)
Inventors
  • RÅNBY, Mats
Agents
  • ZACCO SWEDEN AB
Priority Data
0301785-215.06.2003SE
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COAGULATION TESTS AT AMBIENT TEMPERATURE
(FR) TESTE DE COAGULATION À TEMPÉRATURE AMBIANTE
Abstract
(EN) A method of determining prothrombin time (PT) in a whole blood, anti-coagulated blood, blood plasma or anti-coagulated blood plasma sample at an ambient temperature in the range of 15°C to 45°C is described. The method is performed with liquid reagents and the PT, preferably expressed as International Normalized Ratio (INR), is calculated based on said temperature and the clotting time (CT). A test kit is also described for analysis of PT which comprises temperature recoding means, and one or several separate sealed vessels containing reagents, optionally in lyophilized form for reconstitution prior to use, for clotting one or more defined volumes of whole blood, anti-coagulated blood, blood plasma or anti-coagulated blood plasma sample, and optionally time registration means and volume determining means.
(FR) L'invention concerne un procédé permettant de déterminer le temps de Quick (PT) dans un échantillon de sang total, de sang anti-coagulé, de plasma sanguin, ou de plasma sanguin anti-coagulé à température ambiante comprise entre 15 et 45 °C. Ce procédé est mis en oeuvre au moyen de réactifs liquides et le PT, de préférence exprimé en Rapport International Normalisé (INR), est calculé en fonction de cette température et du temps de coagulation (CT). Une trousse de test permet aussi l'analyse du PT et comprend des moyens d'enregistrement de température, et un ou plusieurs récipients hermétiques séparés contenant des réactifs, facultativement sous forme lyophilisée en vue de la reconstitution avant l'utilisation, afin de coaguler un ou plusieurs volumes définis d'échantillon de sang total, de sang anti-coagulé, de plasma sanguin ou de plasma sanguin anti-coagulé, et facultativement des moyens d'enregistrement du temps et des moyens de détermination du volume.
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