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1. (WO2004104229) INTERNAL CONTROL NUCLEIC ACID MOLECULE FOR NUCLEIC ACID AMPLIFICATION SYSTEMS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2004/104229 International Application No.: PCT/US2004/015175
Publication Date: 02.12.2004 International Filing Date: 14.05.2004
IPC:
C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
VICKERY, Michael, C., L. [US/US]; US
DEPAOLA, Angelo [US/US]; US
BLACKSTONE, George, M. [US/US]; US
Inventors:
VICKERY, Michael, C., L.; US
DEPAOLA, Angelo; US
BLACKSTONE, George, M.; US
Agent:
BRUESS, Steven, C.; Merchant & Gould P.C. P.O. Box 2903 Minneapolis, MN 55402-0903, US
Priority Data:
60/471,12116.05.2003US
Title (EN) INTERNAL CONTROL NUCLEIC ACID MOLECULE FOR NUCLEIC ACID AMPLIFICATION SYSTEMS
(FR) MOLECULE D'ACIDE NUCLEIQUE DE CONTROLE INTERNE POUR SYSTEMES D'AMPLIFICATION D'ACIDE NUCLEIQUE
Abstract:
(EN) The invention provides an internal control nucleic acid molecule including at least one forward primer binding site, at least one reverse primer binding site, and at least one amplifiable region, wherein the forward primer binding site, the reverse primer binding site, and the amplifiable region are all randomly generated. The invention also provides a kit that includes at least one internal control nucleic acid molecule of the invention, at least one forward primer, configured to be complementary to the forward primer binding site of the internal control nucleic acid molecule, and at least one reverse primer, configured to be complementary to the reverse primer binding site of the internal control nucleic acid molecule. The invention also provides methods of using the internal control nucleic acid molecules and kits of the invention.
(FR) Cette invention concerne une molécule d'acide nucléique de contrôle interne comprenant au moins un site de liaison de l'amorce avant, au moins un site de liaison de l'amorce inverse et au moins une région amplifiable, le site de liaison de l'amorce avant, le site de liaison de l'amorce inverse et la région amplifiable étant tous générés de façon aléatoire. Cette invention concerne également une trousse comprenant au moins une molécule d'acide nucléique de contrôle interne de cette invention, au moins une amorce avant, conçue pour être complémentaire au site de liaison de l'amorce avant de la molécule d'acide nucléique de contrôle interne, et au moins une amorce inverse, conçue pour être complémentaire au site de liaison de l'amorce inverse de la molécule d'acide nucléique de contrôle interne. Cette invention concerne en outre des procédés d'utilisation des molécules d'acide nucléique de contrôle interne et des trousses de cette invention.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1625232JP2007500517