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1. (WO2004102198) SELECTION OF B CELLS WITH SPECIFICITY OF INTEREST: METHOD OF PREPARATION AND USE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2004/102198 International Application No.: PCT/EP2004/005208
Publication Date: 25.11.2004 International Filing Date: 14.05.2004
IPC:
C07K 16/00 (2006.01) ,G01N 33/50 (2006.01) ,G01N 33/566 (2006.01) ,G01N 33/569 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
566
using specific carrier or receptor proteins as ligand binding reagent
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
Applicants: BACHMANN, Martin, F.[CH/CH]; CH (UsOnly)
GATTO, Dominique[CH/CH]; CH (UsOnly)
CYTOS BIOTECHNOLOGY AG[CH/CH]; Wagistrasse 25 CH-8952 Schlieren, CH (AllExceptUS)
Inventors: BACHMANN, Martin, F.; CH
GATTO, Dominique; CH
Agent: WICHMANN, Hendrik; Isenbruck Bösl Hörschler Wichmann Huhn Prinzregentenstrasse 68 81675 München, DE
Priority Data:
60/470,44315.05.2003US
Title (EN) SELECTION OF B CELLS WITH SPECIFICITY OF INTEREST: METHOD OF PREPARATION AND USE
(FR) SELECTION DES LYMPHOCYTES B AVEC SPECIFICITE D'INTERET : PROCEDE DE PREPARATION ET UTILISATION
Abstract:
(EN) The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides methods using a composition comprising an ordered and repetitive antigen or antigenic determinant array for visualization and selection of B cells specific for the antigen. These B cells are useful for the production of monoclonal antibodies used for therapy, diagnostic or research purposes.
(FR) Cette invention se rapporte aux domaines de la biologie moléculaire, de la virologie, de l'immunologie et de la médecine. Cette invention concerne des procédés utilisant une composition comprenant un antigène ordonné et répétitif ou un réseau de déterminants antigéniques permettant de visualiser et de sélectionner des lymphocytes B spécifiques de cet antigène. Ces lymphocytes B sont utiles dans la production d'anticorps monoclonaux utilisés à des fins de thérapie, de diagnostic ou de recherche .
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)