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1. (WO2004101803) PROCESS FOR PRODUCING ANTICANCER AGENT LL-D45042
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/101803    International Application No.:    PCT/US2004/014153
Publication Date: 25.11.2004 International Filing Date: 07.05.2004
IPC:
C12P 17/18 (2006.01)
Applicants: WYETH HOLDINGS CORPORATION [US/US]; Five Giralda Farms, Madison, NJ 07940 (US) (For All Designated States Except US).
BERNAN, Valerie, Sue [US/US]; (US) (For US Only).
GRAZIANI, Edmund, Idris [CA/US]; (US) (For US Only)
Inventors: BERNAN, Valerie, Sue; (US).
GRAZIANI, Edmund, Idris; (US)
Agent: MORAN, Daniel, B.; Wyeth, Patent Law Department, Five Giralda Farms, Madison, NJ 07940 (US)
Priority Data:
60/469,719 12.05.2003 US
Title (EN) PROCESS FOR PRODUCING ANTICANCER AGENT LL-D45042
(FR) PROCESSUS DE PRODUCTION D'AGENT ANTICANCEREUX LL-D45042
Abstract: front page image
(EN)The disclosure describes the production of anticancer agent LL-D45042, having the structure (I) by fermentation, to methods for the recovery and concentration of this anticancer agent from crude solutions, and to processes for the purification of this anticancer agent as well as a new microorganism of the species Streptomyces hygroscopicus LL-D45042 and mutants thereof useful in the preparation of this compound.
(FR)La présente invention concerne la production d'un agent anticancéreux LL-D45042 représenté par la structure (I), obtenue par fermentation, des techniques de récupération et de concentration de cet agent anticancéreux à partir de solutions brutes, et des processus de purification de cet agent anticancéreux ainsi qu'un nouveau micro-organisme des espèces Streptomyces hygroscopicus LL-D45042 et des mutants de celui-ci qui convient pour la préparation de ce composé.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)