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1. (WO2004101520) DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES AND THEIR USE AS DELTA OPIOD RECEPTOR AGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/101520    International Application No.:    PCT/GB2004/002071
Publication Date: 25.11.2004 International Filing Date: 13.05.2004
IPC:
C07D 211/70 (2006.01), C07D 401/06 (2006.01), C07D 405/06 (2006.01), C07D 409/06 (2006.01), C07D 417/06 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; SE-151 85 Södertälje (SE) (AE, AG, AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MC, MD, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW only).
ASTRAZENECA UK LIMITED [GB/GB]; 15 Stanhope Gate, London, Greater London W1K 1LN (GB) (MG only).
BROWN, William, L. [CA/CA]; (CA) (For US Only).
GRIFFIN, Andrew [GB/CA]; (CA) (For US Only)
Inventors: BROWN, William, L.; (CA).
GRIFFIN, Andrew; (CA)
Agent: GLOBAL INTELLECTUAL PROPERTY; AstraZeneca AB, SE-151 85 Södertälje (SE)
Priority Data:
0301445-3 16.05.2003 SE
Title (EN) DIARYLMETHYLIDENE PIPERIDINE DERIVATIVES AND THEIR USE AS DELTA OPIOD RECEPTOR AGONISTS
(FR) DERIVES DE DIARYLMETHYLIDENE PIPERIDINE ET LEUR UTILISATION COMME AGONISTES DU RECEPTEUR OPIOIDE DELTA
Abstract: front page image
(EN)Compounds of general formula: (Formula (I)) wherein R1, R2, R3, R4 and R5 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain and anxiety.
(FR)L'invention concerne la préparation de composés de formule générale (I), dans laquelle R1, R2, R3, R4 et R5 sont tels que définis dans la description, ainsi que de leurs sels et des énantiomères de ceux-ci, et des compositions pharmaceutiques renfermant lesdits composés. Ces différents produits sont utilisés en thérapie, en particulier pour la maîtrise de la douleur et de l'anxiété.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)