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Machine translation
1. (WO2004101489) PROCESS FOR THE PREPARATION OF GABAPENTIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/101489    International Application No.:    PCT/IN2003/000246
Publication Date: 25.11.2004 International Filing Date: 21.07.2003
IPC:
C07C 227/16 (2006.01), C07C 229/28 (2006.01)
Applicants: SHASUN CHEMICALS AND DRUGS LIMITED [IN/IN]; 60_Velachery Road, Chennai 600 042, Tamil Nadu (IN) (For All Designated States Except US).
CHANDIRAN, Thakashina, Moorty [IN/IN]; (IN) (For US Only).
SHOBANA, Jothi [IN/IN]; (IN) (For US Only).
SENTHIL, Kumar, Minor [IN/IN]; (IN) (For US Only)
Inventors: CHANDIRAN, Thakashina, Moorty; (IN).
SHOBANA, Jothi; (IN).
SENTHIL, Kumar, Minor; (IN)
Agent: ANAND, Pravin; Anand And Anand Advocates, B-41, Nizamuddin East, New Delhi 110013 (IN)
Priority Data:
416/MAS/2003 19.05.2003 IN
Title (EN) PROCESS FOR THE PREPARATION OF GABAPENTIN
(FR) PROCEDE DE PREPARATION DE GABAPENTINE
Abstract: front page image
(EN)The present invention relates to the process for the preparation of anhydrous Gabapentin of pharmaceutical grade from the Gabapentin acid addition salts. The process consists of neutralizing the said acid addition salts with an organic base in water to get an aqueous solution comprising of Gabapentin and amine acid addition salt dissolved in water. The process further comprises of a method to separate the Gabapentin and the amine acid addition salt from such an aqueous solution and to recover Gabapentin as an anhydrous Gabapentin form II.
(FR)La présente invention concerne le processus de préparation de Gabapentine anhydre de qualité pharmaceutique à partir de sels d'addition d'acides de Gabapentine. Le processus consiste à neutraliser lesdits sels d'addition d'acides avec une base organique dans l'eau pour obtenir une solution aqueuse contenant de la Gabapentine et un sel d'addition d'acide aminé dissous dans l'eau. Le procédé comprend aussi un procédé pour séparer la Gabapentine et le sel d'addition d'acide aminé à partir de cette solution aqueuse et pour récupérer la Gabapentine sous forme de Gabapentine anhydre forme II.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)