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1. (WO2004099781) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G-PROTEIN-COUPLED RECEPTOR RDC1 (RDC1)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/099781    International Application No.:    PCT/EP2004/004278
Publication Date: 18.11.2004 International Filing Date: 22.04.2004
IPC:
A61K 38/00 (2006.01), C07K 14/705 (2006.01), G01N 33/68 (2006.01), G01N 33/74 (2006.01)
Applicants: BAYER HEALTHCARE AG [DE/DE]; 51368 Leverkusen (DE) (For All Designated States Except US).
GOLZ, Stefan [DE/DE]; (DE) (For US Only).
BRÜGGEMEIER, Ulf [DE/DE]; (DE) (For US Only).
SUMMER, Holger [DE/DE]; (DE) (For US Only)
Inventors: GOLZ, Stefan; (DE).
BRÜGGEMEIER, Ulf; (DE).
SUMMER, Holger; (DE)
Common
Representative:
BAYER HEALTHCARE AG; Law and Patents, Patents and Licensing, 51368 Leverkusen (DE)
Priority Data:
03010113.3 05.05.2003 EP
Title (EN) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G-PROTEIN-COUPLED RECEPTOR RDC1 (RDC1)
(FR) APPROCHES DIAGNOSTIQUE ET THERAPEUTIQUE DES MALADIES ASSOCIEES AU RECEPTEUR RDC1 (RDC1) COUPLE A UNE PROTEINE G
Abstract: front page image
(EN)The invention provides a human RDC1 which is associated with the cardiovascular disorders, dermatological disorders, endocrine system and hormone disorders, metabolic diseases, inflammatory diseases, gastrointestinal and liver diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, dermatological disorders, endocrine system and hormone disorders, metabolic diseases, inflammatory diseases, gastrointestinal and liver diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of RDC1 as well as pharmaceutical compositions comprising such compounds.
(FR)L'invention concerne un récepteur RDC1 humain qui est associé aux maladies cardiovasculaires, aux maladies dermatologiques, aux maladies du système endocrinien et aux troubles hormonaux, aux troubles métaboliques, aux maladies inflammatoires, aux maladies gastro-intestinales et hépatiques, ainsi qu'aux maladies hématologiques, respiratoires, neurologiques et urologiques. De plus, l'invention concerne des méthodes de criblage qui permettent d'identifier des composés utilisés dans le traitement ou la prévention des maladies cardiovasculaires, des maladies dermatologiques, des maladies du système endocrinien et des troubles hormonaux, des troubles métaboliques, des maladies inflammatoires, des maladies gastro-intestinales et hépatiques, ainsi que des maladies hématologiques, respiratoires, neurologiques et urologiques. Par ailleurs, l'invention concerne des composés qui se lient au récepteur RDC1 et/ou qui activent ou inhibent son activité ainsi que des compositions pharmaceutiques contenant ces composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)