WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2004099382) METHODS FOR GLOBAL PROFILING GENE REGULATORY ELEMENT ACTIVITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/099382    International Application No.:    PCT/US2004/013664
Publication Date: 18.11.2004 International Filing Date: 29.04.2004
IPC:
C12Q 1/68 (2006.01)
Applicants: GENPATHWAY, INC. [US/US]; 5310 Eastgate Mall, San Diego, CA 92121 (US) (For All Designated States Except US).
WARREN, Mary, E. [US/US]; (US) (For US Only).
ADAMS, Christopher [US/US]; (US) (For US Only).
LABHART, Paul [US/US]; (US) (For US Only).
BALLIVET, Marc [CH/CH]; (CH) (For US Only).
EGAN, Brian, S. [US/US]; (US) (For US Only)
Inventors: WARREN, Mary, E.; (US).
ADAMS, Christopher; (US).
LABHART, Paul; (US).
BALLIVET, Marc; (CH).
EGAN, Brian, S.; (US)
Agent: SERUNIAN, Leslie, A.; Hale and Dorr LLP, 300 Park Avenue, New York, NY 10022 (US)
Priority Data:
10/426,734 30.04.2003 US
Title (EN) METHODS FOR GLOBAL PROFILING GENE REGULATORY ELEMENT ACTIVITY
(FR) METHODES DE PROFILAGE GLOBAL DE L'ACTIVITE D'UN ELEMENT DE REGULATION GENIQUE
Abstract: front page image
(EN)The present invention provides methods for profiling, in a global manner, the activity of gene regulatory elements in cells, including eukaryotic and prokaryotic cells. The methods involve analysis of regulatory element complexes formed under cell-free conditions or within cells (sometimes called 'in vivo'). In accordance with the invention, cells can be in any state of metabolism, resting, growing, normal, mutant, diseased or differentiating. The gene regulatory element activity profiles generated for the cells in different cell populations are compared to determine differences in gene regulatory activity and overall gene expression between or among different types or states of cells.
(FR)La présente invention concerne des méthodes de profilage global de l'activité d'éléments de régulation géniques dans des cellules, y compris des cellules eucaryotes et procaryotes. Ces méthodes consistent à analyser des complexes d'éléments de régulation dans des conditions non cellulaires ou dans des cellules ('in vivo'). Selon l'invention, les cellules peuvent se trouver dans un quelconque état métabolique, au repos, en croissance, à l'état normal, en mutation, malades ou en différenciation. Les profils d'activité des éléments de régulation génique générés pour les cellules dans différentes populations de cellules sont comparés afin de déterminer les différences d'activité de régulation génique et d'expression génique globale entre ou parmi différents types ou états cellulaires.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)