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1. (WO2004099248) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G-PROTEIN-COUPLED RECEPTOR AGTR2 (AGTR2)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/099248    International Application No.:    PCT/EP2004/004276
Publication Date: 18.11.2004 International Filing Date: 22.04.2004
IPC:
A61K 38/00 (2006.01), C07K 14/72 (2006.01)
Applicants: BAYER HEALTHCARE AG [DE/DE]; 51368 Leverkusen (DE) (For All Designated States Except US).
GOLZ, Stefan [DE/DE]; (DE) (For US Only).
BRÜGGEMEIER, Ulf [DE/DE]; (DE) (For US Only).
SUMMER, Holger [DE/DE]; (DE) (For US Only).
THIELE, Ralf [DE/DE]; (DE) (For US Only)
Inventors: GOLZ, Stefan; (DE).
BRÜGGEMEIER, Ulf; (DE).
SUMMER, Holger; (DE).
THIELE, Ralf; (DE)
Common
Representative:
BAYER HEALTHCARE AG; Law and Patents, Patents and Licensing, 51368 Leverkusen (DE)
Priority Data:
03010092.9 05.05.2003 EP
Title (EN) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH G-PROTEIN-COUPLED RECEPTOR AGTR2 (AGTR2)
(FR) PRODUITS DE DIAGNOSTIC ET DE TRAITEMENT DE MALADIES ASSOCIEES AU RECEPTEUR AGTR2 COUPLE AUX PROTEINES G (AGTR2)
Abstract: front page image
(EN)The invention provides a human AGTR2 which is associated with the cardiovascular disorders, metabolic diseases, gastrointestinal and liver diseases, hematological gisorders, cancer disorders, respiratory diseases, neurological disorders and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, metabolic diseases, gastrointestinal and liver diseases, hematological gisorders, cancer disorders, respiratory diseases, neurological disorders and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of AGTR2 as well as pharmaceutical compositions comprising such compounds.
(FR)L'invention concerne un AGTR2 humain associé aux troubles cardiovasculaires, aux maladies métaboliques, aux maladies gastro-intestinales ou hépatiques, aux troubles hématologiques, aux maladies cancéreuses, aux maladies respiratoires, aux troubles neurologiques et aux troubles urologiques. L'invention concerne également des dosages destinés à l'identification de composés utiles dans le traitement ou la prévention de troubles cardiovasculaires, de maladies métaboliques, de maladies gastro-intestinales ou hépatiques, de troubles hématologiques, de maladies cancéreuses, de maladies respiratoires, de troubles neurologiques et de troubles urologiques. L'invention concerne en outre des composés qui se lient à et/ou activent ou inhibent l'activité de AGTR2, ainsi que des compositions pharmaceutiques contenant ces composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)