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1. (WO2004098520) COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/098520    International Application No.:    PCT/US2004/013631
Publication Date: 18.11.2004 International Filing Date: 30.04.2004
Chapter 2 Demand Filed:    01.12.2004    
IPC:
C07D 487/04 (2006.01), C07D 487/14 (2006.01), A01N 43/62 (2006.01), A61K 31/55 (2006.01)
Applicants: IRM LLC [US/US]; PO BOX HM 2899, Hamilton, HM 2899 (BM) (For All Designated States Except US).
WAN, Yongqin [CN/US]; (US) (For US Only).
GRAY, Nathanael, S. [US/US]; (US) (For US Only)
Inventors: WAN, Yongqin; (US).
GRAY, Nathanael, S.; (US)
Agent: REID, Scott, W.; The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121 (US)
Priority Data:
60/467,738 01.05.2003 US
Title (EN) COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
(FR) COMPOSES ET COMPOSITIONS UTILES EN TANT QU'INHIBITEURS DES PROTEINES KINASE
Abstract: front page image
(EN)The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases and disorders associated with kinase activity, particularly diseases associated with the activity of CDK1, CDK2, CDK4, CDK5, GSK3&bgr;, Bcr-abl, Flt-3, c-Kit, PDGFR&bgr;, Src, Mek1 and CK1.
(FR)La présente invention concerne une nouvelle classe de composés, des compositions pharmaceutiques comprenant de tels composés et des procédés d'utilisation de ces composés pour traiter ou prévenir des maladies et des troubles associés à l'activité kinase, notamment les maladies associées à l'activité de CDK1, CDK2, CDK4, CDK5, GSK3ß, Bcr-abl, Flt-3, c-Kit, PDGFRß, Src, Mek1 et CK1.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)