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1. (WO2004098506) TREATMENT FOR AGE-RELATED MACULAR DEGENERATION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2004/098506 International Application No.: PCT/US2004/013332
Publication Date: 18.11.2004 International Filing Date: 30.04.2004
IPC:
A61K 31/00 (2006.01) ,A61K 31/192 (2006.01) ,A61K 31/198 (2006.01) ,A61K 31/203 (2006.01) ,A61K 31/381 (2006.01) ,A61K 31/56 (2006.01) ,A61K 31/575 (2006.01) ,A61K 31/58 (2006.01)
Applicants: SCHWARTZ, Daniel, M.[US/US]; US (UsOnly)
DUNCAN, Keith, G.[US/US]; US (UsOnly)
BAILEY, Kathy, R.[US/US]; US (UsOnly)
KANE, John[US/US]; US (UsOnly)
ISHIDA, Brian, Y.[US/US]; US (UsOnly)
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA[US/US]; 1111 Franklin Street, 12 Floor Oakland, CA 94602-5200, US (AllExceptUS)
Inventors: SCHWARTZ, Daniel, M.; US
DUNCAN, Keith, G.; US
BAILEY, Kathy, R.; US
KANE, John; US
ISHIDA, Brian, Y.; US
Agent: SISTRUNK, Melissa, L.; Fulbrigth & Jaworski, L.L.P. Suite 5100 1301 McKinney Houston, TX 77010-3095, US
Priority Data:
10/428,55102.05.2003US
Title (EN) TREATMENT FOR AGE-RELATED MACULAR DEGENERATION
(FR) TRAITEMENT DE LA DEGENERESCENCE MACULAIRE LIEE A L'AGE
Abstract: front page image
(EN) The present invention addresses the treatment of age-related macular degeneration using regulation of pathogenic mechanisms similar to atherosclerosis. In further specific embodiments, reverse cholesterol transport components, such as transporters and HDL fractions, are utilized as diagnostic and therapeutic targets for age-related macular degeneration. In a specific embodiment, the lipid content of the retinal pigment epithelium, and/or Bruch's membrane is reduced.
(FR) L'invention concerne le traitement de la dégénérescence maculaire liée à l'âge par la régulation de mécanismes pathogènes similaires à l'athérosclérose. Dans d'autres modes de réalisation spécifiques, les composants de transport inverse du cholestérol, tels que les transporteurs et les fractions HDL, sont utilisés en tant que cibles diagnostiques et thérapeutiques pour la dégénérescence maculaire liée à l'âge. Dans un mode de réalisation spécifique, le taux de lipides de l'épithélium pigmentaire rétinien et/ou de la membrane de Bruch est réduit.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)