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Pub. No.:    WO/2004/097411    International Application No.:    PCT/JP2004/005947
Publication Date: 11.11.2004 International Filing Date: 23.04.2004
G01N 33/68 (2006.01)
Applicants: TAKEDA PHARMACEUTICAL COMPANY LIMITED [JP/JP]; 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410045 (JP) (For All Designated States Except US).
ITO, Yasuaki [JP/JP]; (JP) (For US Only).
FUJII, Ryo [JP/JP]; (JP) (For US Only).
KOBAYASHI, Makoto [JP/JP]; (JP) (For US Only).
HINUMA, Shuji [JP/JP]; (JP) (For US Only).
HASHIMOTO, Tadatoshi [JP/JP]; (JP) (For US Only).
TANAKA, Yasuhiro [JP/JP]; (JP) (For US Only)
Inventors: ITO, Yasuaki; (JP).
FUJII, Ryo; (JP).
KOBAYASHI, Makoto; (JP).
HINUMA, Shuji; (JP).
HASHIMOTO, Tadatoshi; (JP).
TANAKA, Yasuhiro; (JP)
Agent: TAKAHASHI, Shuichi; c/o Osaka Plant of Takeda Chemical Industries, Ltd. 17-85, Jusohonmachi 2-chome Yodogawa-ku, Osaka 532-0024 (JP)
Priority Data:
2003-122464 25.04.2003 JP
(JA) 新規スクリーニング方法
Abstract: front page image
(EN)By using a G protein-coupled receptor protein having an amino acid sequence which is the same or substantially the same as the amino aid sequence represented by SEQ ID NO:1 or its salt and an ion chemically available metal element or its salt, an agonist or an antagonist to the above receptor protein or its salt can be efficiently screened.
(FR)Selon l'invention, de par l'utilisation d'une protéine réceptrice couplée aux protéines G présentant une séquence d'acides aminés qui est identique ou sensiblement identique à la séquence d'acides aminés représentée par SEQ ID NO :1 ou d'un sel de ladite protéine et d'un élément à ions métalliques chimiquement disponible ou de son sel, on peut efficacement cribler un agoniste ou un antagoniste de la protéine réceptrice susmentionnée ou de son sel.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)