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Machine translation
1. (WO2004097051) METHODS FOR DIAGNOSING AML AND MDS DIFFERENTIAL GENE EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/097051    International Application No.:    PCT/US2004/013230
Publication Date: 11.11.2004 International Filing Date: 29.04.2004
IPC:
C12Q 1/68 (2006.01), G01N 33/68 (2006.01)
Applicants: WYETH [US/US]; 5 Giralda Farms, Madison, NJ 07940 (US) (For All Designated States Except US).
BURCZYNSKI, Michael, E. [US/US]; (US) (For US Only).
DORNER, Andrew [US/US]; (US) (For US Only).
TWINE, Natalie, C. [US/US]; (US) (For US Only).
TREPICCHIO, William, L. [US/US]; (US) (For US Only).
STOVER, Jennifer [--/US]; (US) (For US Only)
Inventors: BURCZYNSKI, Michael, E.; (US).
DORNER, Andrew; (US).
TWINE, Natalie, C.; (US).
TREPICCHIO, William, L.; (US).
STOVER, Jennifer; (US)
Agent: VAN DYKE, Raymond; Nixon Peabody LLP, 401 9th Street N.W., Washington, D.C. 20004 (US)
Priority Data:
60/466,055 29.04.2003 US
Title (EN) METHODS FOR DIAGNOSING AML AND MDS DIFFERENTIAL GENE EXPRESSION
(FR) TECHNIQUES ET APPAREILS DE DIAGNOSTIC DE LAM ET DE MDS
Abstract: front page image
(EN)Methods, systems and equipment for diagnosing or monitoring the progression or treatment of AML or MDS. This invention identifies a plurality of AML or MDS disease genes which are differentially expressed in bone marrow cells of AML or MDS patients as compared to disease-free humans. These AML or MDS disease genes can be used as molecular markers for detecting the presence or absence of AML or MDS. These genes can also be used for the early identification of MDS patients who eventually progress to AML.
(FR)La présente invention concerne des techniques, des systèmes et un matériel permettant de diagnostiquer ou de surveiller la progression ou le traitement d'une leucémie LAM ou d'un syndrome myélodisplasique (MDS). Cette invention identifie une pluralités de gènes de maladie LAM ou MDS qui sont exprimés différemment dans des cellules de moelle osseuse de patient atteint de LAM ou de MDS comparée à celles de personnes non malades. Ces gènes de maladie LAM ou MDS peuvent être utilisés comme marqueurs moléculaires destinés à détecter la présence ou l'absence de LAM ou de MDS. On peut aussi utiliser ces gènes pour identifier précocement des patients atteints de MDS qui ultérieurement évolue en LAM..
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)