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1. (WO2004096996) MODULATION OF GLUCAGON RECEPTOR EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/096996    International Application No.:    PCT/US2004/012960
Publication Date: 11.11.2004 International Filing Date: 28.04.2004
IPC:
C07H 21/04 (2006.01)
Applicants: ISIS PHARMACEUTICALS, INC. [US/US]; 1896 Rutherford Road, Carlsbad, CA 92008 (US) (For All Designated States Except US).
FREIER, Susan, M. [US/US]; (US) (For US Only)
Inventors: FREIER, Susan, M.; (US)
Agent: BRUSCA, Eric, M.; Marshall, Gerstein & Borun LLP, 6300 Sears Tower, 233 South Wacker Drive, Chicago, IL 60606 (US)
Priority Data:
60/466,311 28.04.2003 US
10/832,622 27.04.2004 US
Title (EN) MODULATION OF GLUCAGON RECEPTOR EXPRESSION
(FR) MODULATION DE L'EXPRESSION DU RECEPTEUR DU GLUCAGON
Abstract: front page image
(EN)Compounds, compositions and methods are provided for modulating the expression of glucagon receptor. The compositions comprise oligonucleotides, targeted to nucleic acid encoding glucagon receptor. Methods of using these compounds for modulation of glucagon receptor expression and for diagnosis and treatment of disease associated with expression of glucagon receptor are provided.
(FR)L'invention concerne des composés, des compositions et des procédés pour moduler l'expression du récepteur du glucagon. Les compositions comprennent des oligonucléotides ciblées sur de l'acide nucléique codant le récepteur du glucagon. La présente invention porte également sur des modes d'utilisation de ces composés pour moduler l'expression du récepteur du glucagon et pour réaliser le diagnostic et le traitement de maladies associées à l'expression du récepteur du glucagon.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)