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1. (WO2004096984) PRESERVATION OF RNA IN A BIOLOGICAL SAMPLE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/096984    International Application No.:    PCT/US2004/011821
Publication Date: 11.11.2004 International Filing Date: 15.04.2004
Chapter 2 Demand Filed:    16.11.2004    
IPC:
C07H 21/02 (2006.01), C07H 21/04 (2006.01), C12Q 1/68 (2006.01)
Applicants: JANSSEN PHARMACEUTICA N.V. [BE/BE]; Turnhoutseweg 30, B-2340 Beerse (BE) (For All Designated States Except US).
KAMME, Fredrik, C. [SE/US]; (US) (For US Only).
MEURERS, Bernhard, H. [DE/US]; (US) (For US Only).
TALANTOV, Dmitri [RU/US]; (US) (For US Only).
YU, Jingxue [CN/US]; (US) (For US Only)
Inventors: KAMME, Fredrik, C.; (US).
MEURERS, Bernhard, H.; (US).
TALANTOV, Dmitri; (US).
YU, Jingxue; (US)
Agent: EVANS, Linda, S.; Johnson & Johnson, Patent Law Dept., One Johnson & Johnson Plaza, New Brunswick, NJ 08933 (US)
Priority Data:
60/465,307 25.04.2003 US
Title (EN) PRESERVATION OF RNA IN A BIOLOGICAL SAMPLE
(FR) PRESERVATION D'ARN DANS UN ECHANTILLON BIOLOGIQUE
Abstract: front page image
(EN)To preserve RNA in a biological sample for analysis, the sample is incubated with an RNA preservative capable of precipitating RNA in an aqueous solution, such as a triphenylmethane dye (e.g., methyl green, crystal violet, pararosaniline, or tris-(4-aminophenyl)methane), cresyl violet, or cobalt ions. RNA preservation may be used in an immunostaining assay and other histochemical methods.
(FR)La présente invention a trait à la préservation d'ARN dans un échantillon biologique pour analyse qui comprend l'incubation de l'échantillon avec un agent de préservation capable d'assurer la précipitation de l'ARN dans une solution aqueuse, telle qu'un colorant de triphénylméthane (par exemple, vert de méthyle, violet de cristal, pararosaniline, ou tris-(4-aminophényl)méthane), violet de crésyle, ou des ions de cobalt. La préservation d'ARN peut être utilisée dans une bioanalyse de marquage immunologique ou d'autres procédés histochimiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)