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1. (WO2004096845) BETA-AMYLOID INHIBITORS AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/096845    International Application No.:    PCT/EP2004/004807
Publication Date: 11.11.2004 International Filing Date: 29.04.2004
IPC:
A61K 38/00 (2006.01), C07K 14/47 (2006.01)
Applicants: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. [NL/NL]; Pietermaai 15, NL-Curaçao (AN) (For All Designated States Except US).
BARBERO, Luca [IT/IT]; (IT) (For US Only).
ESPOSITO, Pierandrea [IT/IT]; (IT) (For US Only).
TRAVERSA, Silvio [IT/IT]; (IT) (For US Only)
Inventors: BARBERO, Luca; (IT).
ESPOSITO, Pierandrea; (IT).
TRAVERSA, Silvio; (IT)
Agent: SERONO INTERNATIONAL S.A.; Intellectual Property, 12, chemin des Aulx, CH-1228 Plan-Les-Ouates (CH)
Priority Data:
03101202.4 30.04.2003 EP
Title (EN) BETA-AMYLOID INHIBITORS AND USE THEREOF
(FR) INHIBITEURS DE BETA-AMYLOIDE ET LEUR UTILISATION
Abstract: front page image
(EN)Peptides and derivatives or analogs thereof are provided for having &bgr;-amyloid aggregation inhibitory activity, useful in the treatment and prevention of diseases such as Alzheimer’s disease, Dementia pugilistica (including head trauma), Hereditary Cerebral Haemorrhage with amyloidosis of the Dutch type (HCHWA-D) and vascular dementia with amyloid angiopathy.
(FR)La présente invention a trait à des peptides et des dérivés ou des analogues de ceux-ci présentant une activité inhibitrice d'agrégation de $g(b)-amyloïdes, utiles dans le traitement et la prévention de maladies telles que la maladie d'Alzheimer, la démence pugilistique (y compris le traumatisme crânien), l'hémorragie cérébrale héréditaire à amylose de type hollandais (HCHWA-D) et la démence vasculaire à angiopathie amyloïde.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)