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1. (WO2004096824) NUCLEOSIDE DERIVATIVE, MODIFIED OLIGONUCLEOTIDE, METHOD FOR THEIR SYNTHESIS AND APPLICATIONS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/096824    International Application No.:    PCT/PL2004/000030
Publication Date: 11.11.2004 International Filing Date: 30.04.2004
IPC:
C07H 19/00 (2006.01), C07H 19/04 (2006.01), C07H 21/00 (2006.01)
Applicants: CENTRUM MIKROBIOLOGII I WIRUSOLOGII POLSKIEJ AKADEMII NAUK [PL/PL]; ul. Lodowa 106, PL-93-232 Lodz (PL) (For All Designated States Except US).
LESNIKOWSKI, Zbigniew, J. [PL/PL]; (PL) (For US Only).
OLEJNICZAK, Agnieszka [PL/PL]; (PL) (For US Only)
Inventors: LESNIKOWSKI, Zbigniew, J.; (PL).
OLEJNICZAK, Agnieszka; (PL)
Agent: WITEK, Rafal; Witek, Twardowska, Sniezko, rzecznicy Patentowi - sp.p., ul. Rudolfa Weigla 12, PL-53-114 Wroclaw (PL)
Priority Data:
P.359949 02.05.2003 PL
P.360228 20.05.2003 PL
Title (EN) NUCLEOSIDE DERIVATIVE, MODIFIED OLIGONUCLEOTIDE, METHOD FOR THEIR SYNTHESIS AND APPLICATIONS THEREOF
(FR) DERIVE DE NUCLEOSIDE, OLIGONUCLEOTIDE MODIFIE, PROCEDE DE SYNTHESE DE CES DERNIERS ET APPLICATIONS ASSOCIEES
Abstract: front page image
(EN)New class of metallated nucleoside and nucleotide conjugates containing metallacarborane cage is provided, also oligonucleotides containing metallacarborane modification are disclosed. Nucleosides, nucleotides and oligonucleotides containing metallacarborane cage can be used among others as modified primers in amplification of RNA and DNA, antisense drugs, boron carriers for BNCT, radiopharmaceuticals bearing a range of isotopes useful in different types of radiotherapy, molecular probes, elements of biosensors, materials for nanotechnology and others.
(FR)L'invention concerne une nouvelle classe de conjugués de nucléosides et de nucléotides métallatés contenant une cage de métallacarborane, ainsi que des oligonucléotides contenant une modification de métallacarborane. Les nucléosides, nucléotides et oligonucléotides contenant une cage de métallacarborane peuvent être utilisés en tant que: amorces modifiées dans l'amplification d'ADN et d'ARN, médicaments antisens, supports de bore pour BNCT, produits pharmaco-radioactifs comportant une plage d'isotopes utiles dans différents types de radiothérapie, sondes moléculaires, éléments de biocapteurs, matériaux pour la nanotechnologie et autres.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)