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1. (WO2004096775) 4,4-DIFLUORO-1,2,3,4-TETRAHYDRO-5H-1-BENZAZEPINE DERIVATIVE OR SALT THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/096775    International Application No.:    PCT/JP2004/005998
Publication Date: 11.11.2004 International Filing Date: 26.04.2004
Chapter 2 Demand Filed:    20.08.2004    
IPC:
C07D 223/16 (2006.01)
Applicants: ASTELLAS PHARMA INC. [JP/JP]; 3-11, Nihonbashi-Honcho 2-chome, Chuo-ku, Tokyo 1038411 (JP) (For All Designated States Except US).
KOSHIO, Hiroyuki [JP/JP]; (JP) (For US Only).
TSUKAMOTO, Issei [JP/JP]; (JP) (For US Only).
KAKEFUDA, Akio [JP/JP]; (JP) (For US Only).
AKAMATSU, Seijiro [JP/JP]; (JP) (For US Only).
SAITOH, Chikashi [JP/JP]; (JP) (For US Only)
Inventors: KOSHIO, Hiroyuki; (JP).
TSUKAMOTO, Issei; (JP).
KAKEFUDA, Akio; (JP).
AKAMATSU, Seijiro; (JP).
SAITOH, Chikashi; (JP)
Agent: NAGAI, Shozo; c/o Astellas Pharma Inc. Intellectual Property 3-11, Nihonbashi-Honcho 2-chome Chuo-ku, Tokyo 103-8411 (JP)
Priority Data:
2003-123032 28.04.2003 JP
2003-401126 01.12.2003 JP
Title (EN) 4,4-DIFLUORO-1,2,3,4-TETRAHYDRO-5H-1-BENZAZEPINE DERIVATIVE OR SALT THEREOF
(FR) DERIVE DE 4,4-DIFLUORO-1,2,3,4-TETRAHYDRO-5H-1-BENZAZEPINE OU SEL DE CELUI-CI
(JA) 4,4-ジフルオロ-1,2,3,4-テトラヒドロ-5H-1-ベンゾアゼピン誘導体又はその塩
Abstract: front page image
(EN)A novel 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative represented by the following formula (I) or a pharmaceutically acceptable salt of the derivative. They are useful as a therapeutic or preventive agent for night pollakisuria and/or diabetes insipidus.
(FR)L'invention concerne un dérivé de 4,4-difluoro-1,2,3,4-tétrahydro-5h-1-benzazépine représenté par la formule suivante (I) ou un sel acceptable sur le plan pharmaceutique de celui-ci, utile comme agent thérapeutique ou préventif pour la pollakiurie nocturne et/ou le diabète insipide.
(JA)not available
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)