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Machine translation
1. (WO2004096245) MUSCLE DERIVED CELLS (MDCS) FOR PROMOTING AND ENHANCING NERVE REPAIR AND REGENERATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/096245    International Application No.:    PCT/US2004/013115
Publication Date: 11.11.2004 International Filing Date: 26.04.2004
IPC:
A61K 35/34 (2006.01), A61P 25/00 (2006.01), C12N 5/077 (2010.01), A61K 35/12 (2006.01)
Applicants: THE UNIVERSITY OF PITTSBURGH [US/US]; The Office of Technology Management, 200 Gardner Steel Conference Center, Thackeray & O'Hara Streets, Pittsburgh, PA 15260 (US) (For All Designated States Except US).
CHANCELLOR, Michael, B. [US/US]; (US) (For US Only).
HUARD, Johnny [US/US]; (US) (For US Only).
MINNERY, Brandon [US/US]; (US) (For US Only)
Inventors: CHANCELLOR, Michael, B.; (US).
HUARD, Johnny; (US).
MINNERY, Brandon; (US)
Agent: SERUNIAN, Leslie, A.; Mintz Levin Cohn Ferris Glovsky & Popeo, P.C., 666 Third Avenue, 24th Floor, New York, NY 10017 (US)
Priority Data:
60/465,846 25.04.2003 US
Title (EN) MUSCLE DERIVED CELLS (MDCS) FOR PROMOTING AND ENHANCING NERVE REPAIR AND REGENERATION
(FR) CELLULES MUSCULAIRES DERIVEES FAVORISANT ET AMELIORANT LA REPARATION ET LA REGENERATION DES NERFS
Abstract: front page image
(EN)The present invention describes methods involving the use of muscle derived cells (MDCs), preferably obtained from skeletal muscle, to support the innervation and repair of damaged tissues and organs, particularly associated with nerve damage or neuropathy. The invention relates to MDCs for use in methods for promoting or enhancing innervation of nerve cells, particularly in the peripheral nervous system, and their ability to contribute to the development of neuronal tissue when MDCs are introduced at or near a tissue or organ site in need of repair due to injury, damage, disease, or dysfunction. Such methods are useful for the treatment of central and peripheral nervous system disorders and to alleviate, abate, or eliminate the symptoms of neurologic or neurodegenerative diseases in animals, particularly mammals, including humans. The methods are also useful for treating both nerve and muscle tissue following injury, damage, or dysfunction to these tissue types.
(FR)L'invention porte sur des méthodes utilisant des cellules musculaires dérivées de préférence de muscles du squelette pour favoriser l'innervation et la réparation de tissus et d'organes endommagés en particulier en cas de lésions nerveuses ou de neuropathies. Lesdites cellules favorisent l'innervation et la réparation des cellules nerveuses, en particulier celles du SNP et contribuent au développement des tissus neuronaux lorsqu'on les introduit dans ou à proximité de tissus ou organes devant être réparés suite à des blessures, des dommages, des maladies ou des dysfonctionnements. Lesdites méthodes peuvent servir à traiter les troubles du SNC et du SNP, et à atténuer, apaiser ou supprimer les symptômes de maladies neurologiques ou neurodégénératives chez l'animal et en particulier chez les mammifères dont l'homme; elles peuvent également traiter les tissus nerveux et musculaires suite à des blessures, des dommages ou des dysfonctionnements de ces types de tissus.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)