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Machine translation
1. (WO2004094671) METHODS AND PRODUCTS FOR IDENTIFICATION AND ASSESSMENT OF TLR LIGANDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/094671    International Application No.:    PCT/US2004/012788
Publication Date: 04.11.2004 International Filing Date: 22.04.2004
IPC:
C07K 14/705 (2006.01)
Applicants: COLEY PHARMACEUTICAL GmbH [DE/DE]; Elisabeth-Selbert-Strasse 9, D-40764 Langenfeld (DE) (For All Designated States Except US).
COLEY PHARMACEUTICAL GROUP, INC. [US/US]; 93 Worcester Street, Suite 101, Wellesley, MA 02481 (US) (For All Designated States Except US).
VOLLMER, Jörg [DE/DE]; (DE) (For US Only).
JURK, Marion [DE/DE]; (DE) (For US Only).
LIPFORD, Grayson, B. [US/US]; (US) (For US Only).
SCHETTER, Christian [DE/DE]; (DE) (For US Only).
FORSBACH, Alexandra [DE/DE]; (DE) (For US Only).
KRIEG, Arthur, M. [US/US]; (US) (For US Only)
Inventors: VOLLMER, Jörg; (DE).
JURK, Marion; (DE).
LIPFORD, Grayson, B.; (US).
SCHETTER, Christian; (DE).
FORSBACH, Alexandra; (DE).
KRIEG, Arthur, M.; (US)
Agent: TREVISAN, Maria, A.; Wolf, Greenfield & Sacks, P.C., 600 Atlantic Avenue, Boston, MA 02210 (US)
Priority Data:
60/464,586 22.04.2003 US
60/464,588 22.04.2003 US
Title (EN) METHODS AND PRODUCTS FOR IDENTIFICATION AND ASSESSMENT OF TLR LIGANDS
(FR) PROCEDES ET PRODUITS POUR IDENTIFIER ET EVALUER DES LIGANDS DES TLR
Abstract: front page image
(EN)The invention provides in part novel screening methods and compositions for identifying and distinguishing between candidate immunomodulatory compounds. The invention further provides methods for assessing biological activity of composition containing a known TLR ligand. These latter methods can be used for quality assessment and selection of various lots of test compositions, including pharmaceutical products for clinical use.
(FR)L'invention concerne de nouvelles compositions et de nouveaux procédés de criblage pour identifier et différencier des composés immunomodulateurs candidats. L'invention concerne en outre des procédés pour évaluer l'activité biologique d'une composition contenant un ligand connu des TLR, ces procédés pouvant être mis en oeuvre pour évaluer la qualité de divers lots de compositions d'essai, notamment des produits pharmaceutiques à usage clinique, et effectuer une sélection.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)