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1. (WO2004085433) POSITIVE ALLOSTERIC MODULATORS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2004/085433 International Application No.: PCT/IB2004/000838
Publication Date: 07.10.2004 International Filing Date: 15.03.2004
Chapter 2 Demand Filed: 16.04.2004
IPC:
C07D 413/12 (2006.01) ,C07D 417/12 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
413
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
417
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/196
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
Applicants:
ROGERS, Bruce, Nelsen [US/US]; US (UsOnly)
PIOTROWSKI, David, Walter [US/US]; US (UsOnly)
MARGOLIS, Brandon, Jerome [US/US]; US (UsOnly)
MYERS, Jason, Kenneth [US/US]; US (UsOnly)
GROPPI, Vincent, Edward, Jr. [US/US]; US (UsOnly)
RUDMANN, Daniel, Gregory [US/US]; US (UsOnly)
PHARMACIA & UPJOHN COMPANY LLC [US/US]; 301 Henrietta Kalamazoo, MI 49001, US (AllExceptUS)
Inventors:
ROGERS, Bruce, Nelsen; US
PIOTROWSKI, David, Walter; US
MARGOLIS, Brandon, Jerome; US
MYERS, Jason, Kenneth; US
GROPPI, Vincent, Edward, Jr.; US
RUDMANN, Daniel, Gregory; US
Agent:
LUMB, J., Trevor; Pfizer Inc. 201 Tabor Road Morris Plains, NJ 07950, US
Priority Data:
60/458,76628.03.2003US
Title (EN) POSITIVE ALLOSTERIC MODULATORS OF THE NICOTINIC ACETYLCHOLINE RECEPTOR
(FR) MODULATEURS ALLOSTERIQUES POSITIFS DU RECEPTEUR NICOTINIQUE DE L'ACETYLCHOLINE
Abstract:
(EN) The invention provides compounds of Formula (I). These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which &agr;7 nAChR is known to be involved.
(FR) L'invention concerne des composés de formule I qui peuvent prendre la forme de sels ou de compositions pharmaceutiques, peuvent se présenter sous une forme énantiomère pure ou sous forme de mélanges racémiques, et sont utiles dans des substances pharmaceutiques utilisées pour traiter des maladies ou des états dans lesquels l'intervention de $g(a)7 nAChR est connue.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)