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1. (WO2004073606) SULFONAMIDE DERIVATIVES AS PPAR MODULATORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/073606    International Application No.:    PCT/US2004/002015
Publication Date: 02.09.2004 International Filing Date: 10.02.2004
IPC:
A61K 31/00 (2006.01), A61K 45/06 (2006.01), C07C 311/13 (2006.01), C07C 311/17 (2006.01), C07C 311/19 (2006.01), C07C 311/29 (2006.01), C07C 317/14 (2006.01), C07C 323/49 (2006.01), C07C 323/52 (2006.01), C07D 207/08 (2006.01), C07D 209/08 (2006.01), C07D 209/48 (2006.01), C07D 213/64 (2006.01), C07D 213/71 (2006.01), C07D 213/74 (2006.01), C07D 215/36 (2006.01), C07D 231/12 (2006.01), C07D 231/18 (2006.01), C07D 263/32 (2006.01), C07D 271/12 (2006.01), C07D 277/36 (2006.01), C07D 307/79 (2006.01), C07D 307/82 (2006.01), C07D 319/18 (2006.01), C07D 333/34 (2006.01), C07D 333/62 (2006.01), C07D 409/04 (2006.01), C07D 409/12 (2006.01), C07D 413/04 (2006.01)
Applicants: ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center, Indianapolis, Indiana 46285 (US) (For All Designated States Except US).
CONNER, Scott, Eugene [US/US]; (US) (For US Only).
GOSSETT, Lynn, Stacy [US/US]; (US) (For US Only).
GREEN, Jonathan, Edward [US/US]; (US) (For US Only).
JONES, Winton, Dennis Jr. [US/US]; (US) (For US Only).
MANTLO, Nathan, Bryan [US/US]; (US) (For US Only).
MATTHEWS, Donald, Paul [US/US]; (US) (For US Only).
MAYHUGH, Daniel, Ray [US/US]; (US) (For US Only).
SMITH, Daryl, Lynn [US/US]; (US) (For US Only).
VANCE, Jennifer, Ann [US/US]; (US) (For US Only).
WANG, Xiaodong [CN/US]; (US) (For US Only).
WARSHAWSKY, Alan, M [US/US]; (US) (For US Only).
WINNEROSKI, Leonard, Larry Jr. [US/US]; (US) (For US Only).
XU, Yanping [CN/US]; (US) (For US Only).
ZHU, Guoxin [CN/US]; (US) (For US Only)
Inventors: CONNER, Scott, Eugene; (US).
GOSSETT, Lynn, Stacy; (US).
GREEN, Jonathan, Edward; (US).
JONES, Winton, Dennis Jr.; (US).
MANTLO, Nathan, Bryan; (US).
MATTHEWS, Donald, Paul; (US).
MAYHUGH, Daniel, Ray; (US).
SMITH, Daryl, Lynn; (US).
VANCE, Jennifer, Ann; (US).
WANG, Xiaodong; (US).
WARSHAWSKY, Alan, M; (US).
WINNEROSKI, Leonard, Larry Jr.; (US).
XU, Yanping; (US).
ZHU, Guoxin; (US)
Agent: JANG, Soonhee; ELI LILLY AND COMPANY, P. O. Box 6288, Indianapolis, Indiana 46206-6288 (US)
Priority Data:
60/448,307 14.02.2003 US
Title (EN) SULFONAMIDE DERIVATIVES AS PPAR MODULATORS
(FR) DERIVES DE SULFONAMIDES UTILISES COMME MODULATEURS DU RECEPTEUR PPAR
Abstract: front page image
(EN)The present invention is directed to a compound of Formula (I):, and pharmaceutically acceptable salts, solvates, hydrates or stereoisomers thereof, which are useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.
(FR)Cette invention se rapporte à un composé représenté par la formule (I), et à des sels, solvates, hydrates ou stéréo-isomères de ce composé, acceptables sur le plan pharmaceutique, qui sont utiles pour traiter ou prévenir les affections médiées par le récepteur activé de la prolifération des peroxysomes (PPAR), telles que le syndrome X, le diabète non insulino-dépendant, l'hyperglycémie, l'hyperlipidémie, l'obésité, les troubles de la coagulation, l'hypertension, l'artériosclérose, et d'autres affections liées au syndrome X et aux maladies cardio-vasculaires .
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)