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1. (WO2004039837) CRH RESPONSIVE GENES IN CNS
Latest bibliographic data on file with the International Bureau
Pub. No.: WO/2004/039837 International Application No.: PCT/EP2003/011792
Publication Date: 13.05.2004 International Filing Date: 23.10.2003
Chapter 2 Demand Filed: 25.03.2004
IPC:
C07K 14/47 (2006.01) ,C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
JANSSEN PHARMACEUTICA N.V. [BE/BE]; Turnhoutseweg 30 B-2340 Beerse, BE (AllExceptUS)
PEETERS, Pieter, Johan [BE/BE]; BE (UsOnly)
GÖHLMANN, Hinrich, Wilhelm, Helmut [DE/BE]; BE (UsOnly)
SWAGEMAKERS, Sigrid, Maria, Alice [NL/NL]; NL (UsOnly)
KASS, Stefan, Ulrich [DE/BE]; BE (UsOnly)
STECKLER, Thomas, Horst, Wolfgang [DE/BE]; BE (UsOnly)
FIERENS, Frederik, Lucien, Pieter [BE/BE]; BE (UsOnly)
Inventors:
PEETERS, Pieter, Johan; BE
GÖHLMANN, Hinrich, Wilhelm, Helmut; BE
SWAGEMAKERS, Sigrid, Maria, Alice; NL
KASS, Stefan, Ulrich; BE
STECKLER, Thomas, Horst, Wolfgang; BE
FIERENS, Frederik, Lucien, Pieter; BE
Common
Representative:
JANSSEN PHARMACEUTICA N.V.; Turnhoutseweg 30 B-2340 Beerse, BE
Priority Data:
PCT/EP02/1227431.10.2002EP
Title (EN) CRH RESPONSIVE GENES IN CNS
(FR) GENES REAGISSANT A L'HORMONE LIBERATRICE DE LA CORTICOTROPINE DANS LE SYSTEME NERVEUX CENTRAL
Abstract:
(EN) The present invention relates generally to therapy and diagnosis of depression. In particular this invention relates to the polypeptides as well as to the polynucleotides encoding these polypeptides, wherein said polypeptides are shown to play a central role in mediating the endocrine response to corticotropin releasing hormone. These polypeptides and polynucleotides are useful in the diagnosis, treatment and/or prevention of depression.
(FR) Cette invention, qui a trait, d'une manière générale, à une méthode thérapeutique et diagnostique de la dépression, concerne, plus précisément, des polypeptides ainsi que des polynucléotides codant ces polypeptides, lesquels polypeptides jouent un rôle éminent, s'agissant de médiatiser une réaction endocrine à l'égard de l'hormone libératrice de la corticotropine. Ces polynucléotides et ces polypeptides se révèlent des plus utiles en matière de diagnostic, de traitement et/ou de prévention de la dépression.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
IL168264EP1558760JP2006519584ES2357832US20060188879CN1708589
CA2499433NZ540084AU2003274072