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1. WO2004039835 - GENES WHOSE EXPRESSION IS INCREASED IN RESPONSE TO STIMULATION BY CORTICOTROPIN-RELEASING HORMONE

Publication Number WO/2004/039835
Publication Date 13.05.2004
International Application No. PCT/EP2003/011793
International Filing Date 23.10.2003
Chapter 2 Demand Filed 25.03.2004
IPC
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
Applicants
  • JANSSEN PHARMACEUTICA N.V. [BE]/[BE] (AllExceptUS)
  • PEETERS, Pieter, Johan [BE]/[BE] (UsOnly)
  • GÖHLMANN, Hinrich, Wilhelm, Helmut [DE]/[BE] (UsOnly)
  • SWAGEMAKERS, Sigrid, Maria, Alice [NL]/[NL] (UsOnly)
  • FIERENS, Frederik, Lucien, Pieter [BE]/[BE] (UsOnly)
Inventors
  • PEETERS, Pieter, Johan
  • GÖHLMANN, Hinrich, Wilhelm, Helmut
  • SWAGEMAKERS, Sigrid, Maria, Alice
  • FIERENS, Frederik, Lucien, Pieter
Common Representative
  • JANSSEN PHARMACEUTICA N.V.
Priority Data
PCT/EP02/1227331.10.2002EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) GENES WHOSE EXPRESSION IS INCREASED IN RESPONSE TO STIMULATION BY CORTICOTROPIN-RELEASING HORMONE
(FR) GENES DONT L'EXPRESSION AUGMENTE EN REACTION A UNE STIMULATION PAR L'HORMONE LIBERATRICE DE LA CORTICOTROPINE
Abstract
(EN)
The present invention relates generally to therapy and diagnosis of depression. In particular this invention relates to the polypeptides as well as to the polynucleotides encoding these polypeptides, wherein said polypeptides are shown to play a central role in mediating the endocrine response to corticotropin releasing hormone. These polypeptides and polynucleotides are useful in the diagnosis, treatment and/or prevention of depression.
(FR)
Cette invention, qui a trait, d'une manière générale, à une méthode thérapeutique et diagnostique de la dépression, concerne, plus précisément, des polypeptides ainsi que des polynucléotides codant ces polypeptides, lesquels polypeptides jouent un rôle éminent, s'agissant de médiatiser une réaction endocrine à l'égard de l'hormone libératrice de la corticotropine. Ces polynucléotides et ces polypeptides se révèlent des plus utiles en matière de diagnostic, de traitement et/ou de prévention de la
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