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1. (WO2004035819) OLIGONUCLEOTIDE ANALOGUES FOR DETECTING AND ANALYZING NUCLEIC ACIDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/035819    International Application No.:    PCT/DK2003/000715
Publication Date: 29.04.2004 International Filing Date: 21.10.2003
IPC:
C07H 21/00 (2006.01), C12N 15/11 (2006.01), C12Q 1/68 (2006.01)
Applicants: EXIQON A/S [DK/DK]; Bygstubben 9, DK-2950 Vedbaek (DK) (For All Designated States Except US).
KAUPPINEN, Sakari [FI/DK]; (DK) (For US Only).
ALSBO, Carsten [DK/DK]; (DK) (For US Only).
NIELSEN, Peter, Stein [DK/DK]; (DK) (For US Only).
JEFFARES, Daniel, Charlton [NZ/DK]; (DK) (For US Only).
MOURIER, Tobias [DK/DK]; (DK) (For US Only).
MØRK, Søren [DK/DK]; (DK) (For US Only).
ARCTANDER, Peter [DK/DK]; (DK) (For US Only).
TOMMERUP, Niels [DK/DK]; (DK) (For US Only).
TOLSTRUP, Niels [DK/DK]; (DK) (For US Only).
VISSING, Henrik [DK/DK]; (DK) (For US Only)
Inventors: KAUPPINEN, Sakari; (DK).
ALSBO, Carsten; (DK).
NIELSEN, Peter, Stein; (DK).
JEFFARES, Daniel, Charlton; (DK).
MOURIER, Tobias; (DK).
MØRK, Søren; (DK).
ARCTANDER, Peter; (DK).
TOMMERUP, Niels; (DK).
TOLSTRUP, Niels; (DK).
VISSING, Henrik; (DK)
Agent: INSPICOS A/S; Bøge Allé 5, P.O. Box 45, DK-2970 Hørsholm (DK)
Priority Data:
60/420,278 21.10.2002 US
PA 2003 00752 19.05.2003 DK
Title (EN) OLIGONUCLEOTIDE ANALOGUES FOR DETECTING AND ANALYZING NUCLEIC ACIDS
(FR) OLIGONUCLEOTIDES UTILES DANS LA DETECTION D'ACIDES NUCLEIQUES D'INTERET
Abstract: front page image
(EN)The invention features improved non-naturally occurring nucleic acids with higher melting temperature than control nucleic acid with 2’ deoxynukleotides, and methods for expression profiling of mRNAs, identifying and profiling of particular mRNA splice variants, and detecting mutations, deletions, or duplications of particular exons or other splice variants, e.g., alterations associated with a disease such as cancer, in a nucleic acid sample, e.g., a biological sample or a patient sample.
(FR)L'invention concerne des acides nucléiques améliorés et des procédés destinés au profilage d'expression des ARNm, pour identifier et profiler des variants épissés déterminés d'ARNm et pour détecter les mutations, les délétions ou les duplications d'exons déterminés ou d'autres variants épissés, p.ex., des altérations associées avec des maladies telles que le cancer dans un échantillon d'acide nucléique, p.ex. dans un échantillon biologique ou un échantillons de patient.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)