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Machine translation
1. (WO2004035787) TRANSPLANTABLE CELL WITH IMMUNE MODULATOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/035787    International Application No.:    PCT/CH2003/000665
Publication Date: 29.04.2004 International Filing Date: 13.10.2003
Chapter 2 Demand Filed:    06.04.2004    
IPC:
A01K 67/027 (2006.01), A61K 35/34 (2006.01), A61K 35/39 (2006.01), C07K 14/54 (2006.01), C12N 5/07 (2010.01), C07K 14/705 (2006.01), C07K 16/00 (2006.01), C07K 16/46 (2006.01), C12N 15/12 (2006.01), C12N 15/62 (2006.01), C12N 15/63 (2006.01), C12N 15/85 (2006.01), C12N 5/071 (2010.01), C12N 5/10 (2006.01), A61K 35/12 (2006.01), A61K 48/00 (2006.01)
Applicants: F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124, CH-4070 Basel (CH) (For All Designated States Except US).
BURCIN, Mark [DE/DE]; (DE) (For US Only).
ESSER, Sybille [DE/DE]; (DE) (For US Only).
RUEDIGER, Manfred [DE/DE]; (DE) (For US Only)
Inventors: BURCIN, Mark; (DE).
ESSER, Sybille; (DE).
RUEDIGER, Manfred; (DE)
Agent: ISENBRUCK BÖSL HÖRSCHLER WICHMANN HUHN; Bösl, Raphael, Prinzregentenstr. 68, 81675 München (DE)
Priority Data:
02022868.0 14.10.2002 EP
Title (DE) TRANSPLANTIERBARE ZELLE MIT IMMUNMODULATOR
(EN) TRANSPLANTABLE CELL WITH IMMUNE MODULATOR
(FR) CELLULE TRANSPLANTABLE
Abstract: front page image
(DE)Die Erfindung betrifft eine humane oder tierische nicht-totipotente Zelle, die mindestens eine Nukleinsäure enthält, welche für mindestens einen Immunmodulator unter der Kontrolle eines durch Zugabe einer Wirksubstanz regulierbaren Genschaltermoleküls kodiert sowie ihre Herstellung und Verwendung zur Transplantation, zur Inhibierung einer Transplantationsabsto&bgr;ungsreaktion sowie zur Prophylaxe und/oder Therapie von Transplantationsfolge- und/oder Autoimmunkranheiten.
(EN)The invention relates to a human or animal non-totipotent cell which contains at least one nucleic acid which codes for at least one immune modulator by controlling a gene switch molecule which is adjusted by adding an active substance. The invention also relates to the production and use thereof in transplants in order to inhibit transplant rejection and also for the prophylaxis and/or therapy of diseases resulting from a transplant and/or auto immune diseases.
(FR)L'invention concerne une cellule humaine ou animale non totipotente, contenant au moins un acide nucléique codant au moins un immunomodulateur sous contrôle d'une molécule de commutation génétique pouvant être régulée par addition d'une substance active. L'invention concerne également la fabrication et l'utilisation de ladite cellule pour la transplantation, l'inhibition d'une réaction de rejet de transplantation, et la prophylaxie et/ou la thérapie de maladies auto-immunes et/ou de maladies faisant suite à une transplantation.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)