WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2004035621) RAD51-BRC REPEAT CRYSTALS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/035621    International Application No.:    PCT/GB2003/004485
Publication Date: 29.04.2004 International Filing Date: 14.10.2003
IPC:
C07K 14/47 (2006.01)
Applicants: CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LTD [GB/GB]; THE OLD SCHOOLS, TRINITY LANE, CAMBRIDGE, Cambridgeshire CB2 1TS (GB) (For All Designated States Except US).
VENKITARAMAN, Ashok [GB/GB]; (GB) (For US Only).
PELLEGRINI, Luca [IT/GB]; (GB) (For US Only).
BLUNDELL, Tom [GB/GB]; (GB) (For US Only).
YU, David [US/GB]; (GB) (For US Only).
LO, Thomas [GB/GB]; (GB) (For US Only).
BATES, Debbie [GB/GB]; (GB) (For US Only).
SHIVJI, Mahmud [GB/GB]; (GB) (For US Only).
ANAND, Shubha [IN/GB]; (GB) (For US Only).
LEE, MiYoung [KR/GB]; (GB) (For US Only)
Inventors: VENKITARAMAN, Ashok; (GB).
PELLEGRINI, Luca; (GB).
BLUNDELL, Tom; (GB).
YU, David; (GB).
LO, Thomas; (GB).
BATES, Debbie; (GB).
SHIVJI, Mahmud; (GB).
ANAND, Shubha; (GB).
LEE, MiYoung; (GB)
Agent: GILL, Stephen, C.; Mewburn Ellis, York House, 23 Kingsway, London, Greater London WC2B 6HP (GB).
ARMITAGE, Ian, M.; Mewburn Ellis, York House 23 Kingsway, London, Greater London WC2B 6HP (GB).
BRASNETT, Adrian, H.; Mewburn Ellis, York House 23 Kingsway, London, Greater London WC2B 6HP (GB).
CALDERBANK, T., Roger; Mewburn Ellis, York House 23 Kingsway, London, Greater London WC2B 6HP.
COLEIRO, Raymond; Mewburn Ellis, York House 23 Kingsway, London, Greater London WC2B 6HP.
CRIPPS, Joanna, E.; Mewburn Ellis, York House 23 Kingsway, London, Greater London WC2B 6HP
Priority Data:
0223860.8 14.10.2002 GB
Title (EN) RAD51-BRC REPEAT CRYSTALS
(FR) METHODES ET MOYENS FAISANT APPEL A DES POLYPEPTIDES
Abstract: front page image
(EN)The structure of a RAD51-BRC repeat sequence complex structure is provided. The structure can be used in modelling the interaction of molecular structures such as potential pharmaceutical compounds. Mutant RAD51 and BRCA2 polypeptides and RAD51-BRC repeat sequence chimaera proteins and are also provided. The mutants may be used in assays for finding compounds which interact with or form part of a RAD51 pathway, and the chimaeras can be used to form crystals which may be analysed by X-ray crystallography.
(FR)L'invention concerne la structure d'une structure complexe d'une séquence répétée de RAD51-BRC. Cette structure peut être utilisée dans la modélisation de l'interaction de structures moléculaires telles que des composés pharmaceutiquement potentiels. L'invention concerne également des mutants de RAD51 et des protéines chimères à séquence répétée de RAD51-BRC et de polypeptides de BRCA2. Lesdits mutants peuvent être utilisés dans des analyses de recherche de composés qui interagissent avec ou font partie d'une voie RAD51, et les chimères peuvent être utilisées pour former des cristaux qui peuvent être analysés par cristallographie aux rayons X.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)