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1. (WO2004035549) BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/035549    International Application No.:    PCT/US2003/032823
Publication Date: 29.04.2004 International Filing Date: 16.10.2003
Chapter 2 Demand Filed:    30.04.2004    
IPC:
C07D 235/30 (2006.01), C07D 401/04 (2006.01), C07D 401/12 (2006.01), C07D 401/14 (2006.01), C07D 403/12 (2006.01), C07D 403/14 (2006.01), C07D 405/14 (2006.01), C07D 409/14 (2006.01), C07D 417/12 (2006.01), C07D 417/14 (2006.01), C07D 471/04 (2006.01)
Applicants: AMGEN INC. [US/US]; One Amgen Center Drive, Thousand Oak, CA 91320-1799 (US) (For All Designated States Except US).
BALAN, Chenera [IN/US]; (US) (For US Only).
BO, Yunxin [CN/US]; (US) (For US Only).
DOMINGUEZ, Celia [US/US]; (US) (For US Only).
FOTSCH, Christopher, H. [US/US]; (US) (For US Only).
GORE, Vijay, K. [IN/US]; (US) (For US Only).
MA, Vu Van [VN/US]; (US) (For US Only).
NORMAN, Mark, H. [US/US]; (US) (For US Only).
OGNYANOV, Vassil, I. [US/US]; (US) (For US Only).
QIAN, Yi-xin [CN/US]; (US) (For US Only).
WANG, Xianghong [CN/US]; (US) (For US Only).
XI, Ning [CN/US]; (US) (For US Only).
XU, Shimin [CN/US]; (US) (For US Only)
Inventors: BALAN, Chenera; (US).
BO, Yunxin; (US).
DOMINGUEZ, Celia; (US).
FOTSCH, Christopher, H.; (US).
GORE, Vijay, K.; (US).
MA, Vu Van; (US).
NORMAN, Mark, H.; (US).
OGNYANOV, Vassil, I.; (US).
QIAN, Yi-xin; (US).
WANG, Xianghong; (US).
XI, Ning; (US).
XU, Shimin; (US)
Agent: ODRE, Steven; Amgen, Inc., One Amgen Center Drive, M/S 27-4-A, Thousand Oaks, CA 91320-1799 (US)
Priority Data:
60/419,791 17.10.2002 US
Title (EN) BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS
(FR) DERIVES DE BENZIMIDAZOLES ET UTILISATION DE CEUX-CI EN TANT QUE LIGANDS DU RECEPTEUR VANILLOIDE
Abstract: front page image
(EN)Compounds of formula (I) are useful in the treatment of vanilloid-receptor-meditated diseases, such as inflammatory or neuropathic pain and diseases involving sensory nerve function such as asthma, rheumatoid arthritis, osteoarthritis, inflammatory bowel disorders, urinary incontinence, migraine and psoriasis.
(FR)L'invention concerne des composés représentés par la formule (I) utilisés dans le traitement de maladies induites par le récepteur vanilloïde, telles que la douleur inflammatoire ou neuropathique, ainsi que des maladies impliquant la fonction du nerf sensoriel, telles que l'asthme, la polyarthrite rhumatoïde, l'ostéoarthrose, les troubles du colon irritable, l'incontinence, la migraine et le psoriasis.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)