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Pub. No.:    WO/2004/034985    International Application No.:    PCT/US2003/032625
Publication Date: 29.04.2004 International Filing Date: 15.10.2003
Chapter 2 Demand Filed:    12.04.2004    
A61K 31/47 (2006.01), C07D 453/02 (2006.01)
Applicants: SMITHKLINE BEECHAM CORPORATION [US/US]; One Franklin Plaza, Philadelphia, PA 19101 (US) (For All Designated States Except US).
BURGESS, Joelle, L. [US/US]; (US) (For US Only).
CALLAHAN, James, F. [US/US]; (US) (For US Only).
HAMAJIMA, Toshihiro [JP/JP]; (JP) (For US Only).
IDA, Satoru [JP/NE]; (JP) (For US Only).
TANG, Jun [CN/JP]; (JP) (For US Only).
MORI, Ichiro [JP/JP]; (JP) (For US Only)
Inventors: BURGESS, Joelle, L.; (US).
CALLAHAN, James, F.; (US).
HAMAJIMA, Toshihiro; (JP).
IDA, Satoru; (JP).
TANG, Jun; (JP).
MORI, Ichiro; (JP)
Agent: LEVY, David, J.; GlaxoSmithKline, Corporate Intellectual Property Department, Five Moore Drive, PO Box 13398, Research Triangle Park, NC 27709 (US)
Priority Data:
60/418,915 16.10.2002 US
Abstract: front page image
(EN)3-carboxy quinoline derivatives, which are useful as YAK3 inhibitors are described herein. The described invention also includes methods of making such 3-carboxy quinoline derivatives as well as methods of using the same in the treatment of diseases mediated by inappropriate YAK3 activity.
(FR)L'invention concerne des dérivés de 3-carboxy quinoléine, utiles en tant qu'inhibiteurs de YAK3. L'invention concerne également des procédés de fabrication de ces dérivés ainsi que leurs procédés d'utilisation dans le traitement de maladies liées à l'activité de YAK3.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)