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1. (WO2004031356) RECOMBINANT INTRACELLULAR PATHOGEN IMMUNOGENIC COMPOSITIONS AND METHODS FOR USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/031356    International Application No.:    PCT/US2003/030994
Publication Date: 15.04.2004 International Filing Date: 30.09.2003
IPC:
A61K 38/00 (2006.01), C07K 14/35 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; Office of Technology Transfer, 11th Floor, 1111 Franklin Street, Oakland, CA 94607-5200 (US) (For All Designated States Except US).
HORWITZ, Marcus, A. [US/US]; (US) (For US Only).
HARTH, Gunter [US/US]; (US) (For US Only).
TULLIUS, Michael, V. [US/US]; (US) (For US Only)
Inventors: HORWITZ, Marcus, A.; (US).
HARTH, Gunter; (US).
TULLIUS, Michael, V.; (US)
Agent: CULLMAN, Louis, C.; Stradling Yocca Carlson & Rauth, Suite 1600, 660 Newport Center Drive, Newport Beach, CA 92660 (US)
Priority Data:
10/261981 30.09.2002 US
10/439611 15.05.2003 US
Title (EN) RECOMBINANT INTRACELLULAR PATHOGEN IMMUNOGENIC COMPOSITIONS AND METHODS FOR USE
(FR) COMPOSITIONS IMMUNOGENES DE PATHOGENES INTRACELLULAIRES DE RECOMBINAISON ET LEURS METHODES D'UTILISATION
Abstract: front page image
(EN)Immunogenic compositions comprising recombinant attenuated intracellular pathogens that have been transformed to express recombinant immunogenic antigens of the same or other intracellular pathogens are provided. Exemplary immunogenic compositions include, but are not limited to attenuated recombinant Mycobacteria expressing the major extracellular non-fusion proteins of Mycobacteria and/or other intracellular pathogens. Other embodiments are provided wherein the recombinant attenuated intracellular pathogen is auxotrophic.
(FR)L'invention concerne des compositions immunogènes comprenant des pathogènes intracellulaires atténués de recombinaison qui ont été transformés pour exprimer des antigènes immunogènes de recombinaison desdits pathogènes ou d'autres pathogènes intracellulaires. Les compositions immunogènes prises en exemple comprennent, notamment, des mycobactéries atténuées de recombinaison exprimant les principales protéines extracellulaires non fusionnées des mycobactéries et/ou d'autres pathogènes intracellulaires. Dans d'autres modes de réalisation, le pathogène intracellulaire atténué de recombinaison est auxotrophe.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)