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Machine translation
1. (WO2004031145) LACTAM-CONTAINING DIAMINOALKYL, BETA-AMINOACIDS, ALPHA-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/031145    International Application No.:    PCT/US2003/031079
Publication Date: 15.04.2004 International Filing Date: 01.10.2003
Chapter 2 Demand Filed:    22.04.2004    
IPC:
C07D 211/76 (2006.01), C07D 213/64 (2006.01), C07D 213/75 (2006.01), C07D 401/12 (2006.01), C07D 405/12 (2006.01), C07D 409/12 (2006.01)
Applicants: BRISTOL-MYERS SQUIBB COMPANY [US/US]; P.O BOX 4000, ROUTE 206 and PROVINCELINE ROAD, PRINCETON, NJ 08543-4000 (US) (For All Designated States Except US).
QIAO, Jennifer, X. [CN/US]; (US) (For US Only).
HAN, Wei [CN/US]; (US) (For US Only)
Inventors: QIAO, Jennifer, X.; (US).
HAN, Wei; (US)
Agent: BELFIELD, Jing, S., Ph.D.; Bristol-Myers Squibb Company, P.O. Box 4000, Route 206 and Provinceline Road, Princeton, NJ 08543-4000 (US)
Priority Data:
60/415,366 02.10.2002 US
60/417,208 09.10.2002 US
Title (EN) LACTAM-CONTAINING DIAMINOALKYL, BETA-AMINOACIDS, ALPHA-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS
(FR) DIAMINOALKYLE CONTENANT DU LACTAME, ACIDES AMINES BETA, ACIDES AMINES ALPHA ET LEURS DERIVES UTILISES EN TANT QU'INHIBITEURS DU FACTEUR XA
Abstract: front page image
(EN)The present application describes lactam-containing diaminoalkyl, b-aminoacids, a-aminoacids and derivatives thereof of Formula ( I): P-M-M1 or pharmaceutically acceptable salt forms thereof, wherein M is a linear core. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
(FR)L'invention concerne un diaminoalkyle contenant du lactame, des acides aminés $g(b), des acides aminés $g(a) et des dérivés de ces composés représentés par la formule (I), P-M-M1, ou des sels pharmaceutiquement acceptables desdits composés. Dans ladite formule, M représente un noyau linéaire. Les composés sont utiles en tant qu'inhibiteurs des sérine protéases du type trypsine, notamment du facteur Xa.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)