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1. (WO2004031143) NOVEL COMBINATION OF A FACTOR XA INHIBITOR AND CLOPIDOGREL

Pub. No.:    WO/2004/031143    International Application No.:    PCT/US2003/029948
Publication Date: Apr 15, 2004 International Filing Date: Sep 25, 2003
IPC: A61K 45/06
Applicants: BRISTOL-MYERS SQUIBB COMPANY
WONG, Pancras
KNABB, Robert
Inventors: WONG, Pancras
KNABB, Robert
Title: NOVEL COMBINATION OF A FACTOR XA INHIBITOR AND CLOPIDOGREL
Abstract:
The present application describes methods of using a combination of 1-(3'-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-5-[[4-[(2'-dimethylaminomethyl)imidazol-1'-yl]-2-fluorophenyl]aminocarbonyl]pyrazole-hydrochloricacid salt, a factor Xa inhibitor, and Clopidogrel asanticoagulant agents for treatment of thromboembolic disorders and pharmaceutical compositions containing the same.