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Machine translation
1. (WO2004031139) CYCLOHEXYL SULPHONES AS GAMMA-SECRETASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/031139    International Application No.:    PCT/GB2003/004196
Publication Date: 15.04.2004 International Filing Date: 25.09.2003
Chapter 2 Demand Filed:    04.03.2004    
IPC:
A61K 31/10 (2006.01), C07C 317/30 (2006.01), C07D 213/70 (2006.01), C07D 213/74 (2006.01), C07D 231/18 (2006.01), C07D 233/42 (2006.01), C07D 249/12 (2006.01), C07D 257/04 (2006.01), C07D 261/10 (2006.01), C07D 275/03 (2006.01), C07D 277/36 (2006.01), C07D 295/088 (2006.01), C07D 307/64 (2006.01), C07D 333/34 (2006.01)
Applicants: MERCK SHARP & DOHME LIMITED [GB/GB]; Hertford Road, Hoddesdon, Hertfordshire EN11 9BU (GB) (For All Designated States Except US).
CHURCHER, Ian [GB/GB]; (GB) (For US Only).
HARRISON, Timothy [GB/GB]; (GB) (For US Only).
KERRAD, Sonia [FR/GB]; (GB) (For US Only).
NADIN, Alan, John [GB/GB]; (GB) (For US Only).
OWENS, Andrew, Pate [GB/GB]; (GB) (For US Only).
SHAW, Duncan, Edward [GB/GB]; (GB) (For US Only).
THOMSON, Joanne [GB/GB]; (GB) (For US Only).
WILLIAMS, Susannah [GB/GB]; (GB) (For US Only)
Inventors: CHURCHER, Ian; (GB).
HARRISON, Timothy; (GB).
KERRAD, Sonia; (GB).
NADIN, Alan, John; (GB).
OWENS, Andrew, Pate; (GB).
SHAW, Duncan, Edward; (GB).
THOMSON, Joanne; (GB).
WILLIAMS, Susannah; (GB)
Agent: BUCHAN, Gavin, MacNicol; Merck & Co., Inc., European Patent Department, Terlings Park, Eastwick Road, Harlow, Essex CM20 2QR (GB)
Priority Data:
0223038.1 04.10.2002 GB
Title (EN) CYCLOHEXYL SULPHONES AS GAMMA-SECRETASE INHIBITORS
(FR) SULFONES CYCLOHEXYLIQUES TELS QUE DES INHIBITEURS DE GAMMA-SECRETASE
Abstract: front page image
(EN)Compounds of formula (I) inhibit the processing of APP by gamma-secretase, and hence are useful in treating or preventing Alzheimer's disease.
(FR)L'invention concerne des composés de formule (I). Ces composés inhibent la transformation de la protéine précurseur amyloïde (APP) par gamma-sécrétase. Ces composés sont donc utiles dans le traitement et la prévention de la maladie d'Alzheimer.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)