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1. (WO2004030657) SPHEROIDS, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/030657    International Application No.:    PCT/FR2003/002909
Publication Date: 15.04.2004 International Filing Date: 03.10.2003
Chapter 2 Demand Filed:    26.04.2004    
IPC:
A61K 9/20 (2006.01), A61K 9/50 (2006.01)
Applicants: ETHYPHARM [FR/FR]; 21, rue Saint-Mathieu, F-78550 Houdan (FR) (For All Designated States Except US).
CHENEVIER, Philippe [FR/CA]; (CA) (For US Only).
MARECHAL, Dominique [FR/FR]; (FR) (For US Only)
Inventors: CHENEVIER, Philippe; (CA).
MARECHAL, Dominique; (FR)
Agent: MARTIN, Jean-Jacques; Cabinet Regimbeau, 20, rue de Chazelles, F-75847 Paris Cedex 17 (FR)
Priority Data:
02/12333 04.10.2002 FR
Title (EN) SPHEROIDS, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS
(FR) SPHEROIDES PROCEDE DE PREPARATION ET COMPOSITIONS PHARMACEUTIQUES
Abstract: front page image
(EN)The invention relates to a directly-compressible gastro-resistant spheroid. The inventive spheroid is characterised in that it comprises: (i) a core containing one or more active substances; (ii) a flexible, deformable film which is used directly to coat the aforementioned core and which comprises an enteric polymer and a mixture of saturated and/or unsaturated polyglycosylated glycerides, the fatty acids of which include at least 8 carbon atoms; and an outer water-dispersible layer containing at least one disintegrating agent.
(FR)La présente invention concerne un sphéroïde gastro­résistant directement compressible, caractérisé en ce qu'il comprend -un noyau contenant un ou plusieurs principe(s) actif(s) directement enrobé par, -un film souple et déformable, comprenant un polymère entérique et un mélange de glycérides polyglycosylés saturés et/ou insaturés dont les acides gras comprennent au moins 8 atomes de carbone,une couche externe hydrodispersible contenant au moins un agent désintégrant.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)