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1. (WO2004030618) METHODS AND REAGENTS FOR THE TREATMENT OF DISEASES AND DISORDERS ASSOCIATED WITH INCREASED LEVELS OF PROINFLAMMATORY CYTOKINES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/030618    International Application No.:    PCT/US2003/030156
Publication Date: 15.04.2004 International Filing Date: 24.09.2003
Chapter 2 Demand Filed:    21.04.2004    
IPC:
A61K 31/00 (2006.01), A61K 38/13 (2006.01), A61K 45/06 (2006.01)
Applicants: COMBINATORX, INCORPORATED [--/--]; 650 Albany Street, Boston, MA 02118 (US) (For All Designated States Except US).
JOST-PRICE, Edward, Roydon [US/US]; (US) (For US Only).
MANIVASAKAM, Palaniyandi [US/US]; (US).
SMITH, Brendan [US/US]; (US).
FONG, Jason [US/US]; (US).
AUSPITZ, Benjamin, A. [US/US]; (US).
NICHOLS, M., James [US/US]; (US).
KEITH, Curtis [CA/US]; (US).
ZIMMERMANN, Grant, R. [US/US]; (US).
BRASHER, Bradley, B. [US/US]; (US).
SACHS, Noah [US/US]; (US).
CHAPPELL, Todd, W. [US/US]; (US)
Inventors: JOST-PRICE, Edward, Roydon; (US).
MANIVASAKAM, Palaniyandi; (US).
SMITH, Brendan; (US).
FONG, Jason; (US).
AUSPITZ, Benjamin, A.; (US).
NICHOLS, M., James; (US).
KEITH, Curtis; (US).
ZIMMERMANN, Grant, R.; (US).
BRASHER, Bradley, B.; (US).
SACHS, Noah; (US).
CHAPPELL, Todd, W.; (US)
Agent: CLARK, Paul, T.; Clark & Elbing LLP, 101 Federal Street, Boston, MA 02110 (US)
Priority Data:
60/413,040 24.09.2002 US
60/417,261 09.10.2002 US
60/427,526 19.11.2002 US
60/427,424 19.11.2002 US
60/464,753 23.04.2003 US
Title (EN) METHODS AND REAGENTS FOR THE TREATMENT OF DISEASES AND DISORDERS ASSOCIATED WITH INCREASED LEVELS OF PROINFLAMMATORY CYTOKINES
(FR) METHODES ET REACTIFS DESTINES AU TRAITEMENT DE MALADIES ET DE TROUBLES ASSOCIES A DES NIVEAUX ACCRUS DE CYTOKINES PRO-INFLAMMATOIRES
Abstract: front page image
(EN)The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering an SSRI or analog or metabolite thereof and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing an SSRI or analog or metabolite thereof and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder.
(FR)L'invention concerne une méthode de traitement d'un patient diagnostiqué, ou susceptible de développer un trouble immuno-inflammatoire par administration à ce patient d'un SSRI (inhibiteur sélectif de recaptage de la sérotonine) ou d'un analogue, ou d'un métabolite de ce produit, et, éventuellement, d'un corticostéroïde ou d'un autre composé. Elle concerne aussi une composition pharmaceutique contenant un SSRI, ou un analogue, ou un métabolite de ce produit et un corticostéroïde ou un autre composé, destinée au traitement ou à la prévention d'un trouble immuno-inflammatoire.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)