WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2004030522) DIAGNOSIS AND MONITORING OF DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/030522    International Application No.:    PCT/US2003/031226
Publication Date: 15.04.2004 International Filing Date: 02.10.2003
Chapter 2 Demand Filed:    03.05.2004    
IPC:
A01N 1/00 (2006.01), A01N 1/02 (2006.01), A01N 37/18 (2006.01), A61B 1/00 (2006.01), A61K 38/00 (2006.01), A61K 39/395 (2006.01), C07K 16/18 (2006.01), G01N 33/48 (2006.01), G01N 33/483 (2006.01), G01N 33/50 (2006.01), G01N 33/53 (2006.01), G01N 33/576 (2006.01)
Applicants: DMI BIOSCIENCES, INC. [US/US]; 3601 S. Clarkson Street, Suite 420, Englewood, CO 80110 (US)
Inventors: BAR-OR, David; (US).
BAR-OR, Raphael; (US)
Agent: CONNELL, Gary, J.; Sheridan Ross P.C., Suite 1200, 1560 Broadway, Denver, CO 80202-5141 (US)
Priority Data:
60/415,908 02.10.2002 US
60/489,039 21.07.2003 US
60/503,185 15.09.2003 US
Title (EN) DIAGNOSIS AND MONITORING OF DISEASES
(FR) DIAGNOSTIC ET CONTROLE DE MALADIES
Abstract: front page image
(EN)The present invention relates to the diagnosis and monitoring of diseases and conditions by quantifying markers, including degradation products of disease-associated proteins, such as diketopiperazines composed of the two N-terminal amino acids or the two C-terminal amino acids of such proteins. The methods are useful for diagnosing or monitoring various diseases, including multiple sclerosis, Alzheimer's disease and ischemia. The invention further provides binding partners specific for the markers and compositions and kits for conducting the methods of the invention.
(FR)L'invention concerne le diagnostic et le contrôle de maladies et d'états au moyen de marqueurs de quantification, y compris des produits de dégradation de protéines associées à la maladie, telles que des dikétopipérazines composées de deux acides aminés à terminaison N ou des deux acides aminés à terminaison C de ces protéines. Ces méthodes sont utiles pour diagnostiquer ou contrôler différentes maladies, y compris la sclérose en plaques, la maladie d'Alzheimer et l'ischémie. Elle concerne, de plus, des partenaires de liaison spécifiques pour ces marqueurs, des compositions et des trousses servant à mettre en application ces méthodes.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)