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1. (WO2004029617) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN PHOSPHODIESTERASE 11A (PDE11A)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/029617    International Application No.:    PCT/EP2003/010376
Publication Date: 08.04.2004 International Filing Date: 18.09.2003
IPC:
C12Q 1/44 (2006.01), G01N 33/574 (2006.01), G01N 33/68 (2006.01)
Applicants: BAYER HEALTHCARE AG [DE/DE]; 51368 Leverkusen (DE) (For All Designated States Except US).
GOLZ, Stefan [DE/DE]; (DE) (For US Only).
BRÜGGEMEIER, Ulf [DE/DE]; (DE) (For US Only).
GEERTS, Andreas [DE/DE]; (DE) (For US Only)
Inventors: GOLZ, Stefan; (DE).
BRÜGGEMEIER, Ulf; (DE).
GEERTS, Andreas; (DE)
Common
Representative:
BAYER HEALTHCARE AG; Law and Patents, Patents and Licensing, 51368 Leverkusen (DE)
Priority Data:
02021365.8 24.09.2002 EP
Title (EN) DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN PHOSPHODIESTERASE 11A (PDE11A)
(FR) DIAGNOSTIC ET THERAPEUTIQUE DE MALADIES ASSOCIEES A LA PHOSPHODIESTERASE HUMAINE 11A (PDE11A)
Abstract: front page image
(EN)The invention provides a human PDE11A which is associated with the disorders of the peripheral and central nervous system (Alzheimer), cardiovascular diseases, cancer (thyroid tumor, lung tumor, colon tumor), liver disease (liver cirrhosis) and genito-urinary diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of disorders of the peripheral and central nervous system, cardiovascular diseases, cancer, liver disease and genito-urinary diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of PDE11A as well as pharmaceutical compositions comprising such compounds.
(FR)La présente invention concerne une PDE11A humaine qui est associée aux troubles du système nerveux central et périphérique, aux maladies cardiovasculaires, au cancer, aux maladies du foie et aux maladies génito-urinaires. L'invention concerne également des analyses permettant d'identifier des composés utiles pour le traitement ou la prévention des troubles du système nerveux périphérique et central, des maladies cardiovasculaires, du cancer, des maladies du foie et des maladies génito-urinaires. L'invention se rapporte enfin à des composés qui lient et/ou activent ou inhibent l'activité de PDE11A, et à des compositions pharmaceutiques contenant lesdits composés.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)