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1. (WO2004028563) A VACCINE ENHANCING THE PROTECTIVE IMMUNITY TO HEPATITIS C VIRUS USING PLASMID DNA AND RECOMBINANT ADENOVIRUS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/028563    International Application No.:    PCT/KR2003/001951
Publication Date: 08.04.2004 International Filing Date: 24.09.2003
Chapter 2 Demand Filed:    07.04.2004    
IPC:
A61K 39/12 (2006.01), A61K 39/29 (2006.01)
Applicants: GENEXINE INC. [KR/KR]; 1403 Miwon Bldg., 43 Yeouido-dong , Yeongdeungpo-ku, 150-889 Seoul (KR) (For All Designated States Except US).
POSTECH FOUNDATION [KR/KR]; San 31 Hyoja-dong, Nam-ku, Pohang-si, 790-784 Gyeongsangbuk-do (KR) (For All Designated States Except US).
DONG-A PHARM. CO., LTD. [KR/KR]; 252 Yongdu2-dong, Dongdaemun-ku, 130-823 Seoul (KR) (For All Designated States Except US).
DAEWOONG CO., LTD. [KR/KR]; 223-23 Sangdaewon-dong, Jungwon-ku, Seongnam-si, 462-807 Kyunggi-do (KR) (For All Designated States Except US).
POSCO [KR/KR]; 1 Goedong, Nam-ku, Pohang-si, 790-704 Gyeongsangbuk-do (KR) (For All Designated States Except US).
SUNG, Young Chul [KR/KR]; (KR) (For US Only).
YOUN, Jin-Won [KR/KR]; (KR) (For US Only).
YANG, Se-Hwan [KR/KR]; (KR) (For US Only).
PARK, Su-Hyung [KR/KR]; (KR) (For US Only).
LEE, Chang Geun [KR/KR]; (KR) (For US Only)
Inventors: SUNG, Young Chul; (KR).
YOUN, Jin-Won; (KR).
YANG, Se-Hwan; (KR).
PARK, Su-Hyung; (KR).
LEE, Chang Geun; (KR)
Agent: Lee, Won-Hee; 8th Fl., Sung-ji Heights II, 642-16 Yoksam-dong, Kangnam-ku, 135-080 Seoul (KR)
Priority Data:
10-2002-0058712 27.09.2002 KR
10-2002-0068496 06.11.2002 KR
Title (EN) A VACCINE ENHANCING THE PROTECTIVE IMMUNITY TO HEPATITIS C VIRUS USING PLASMID DNA AND RECOMBINANT ADENOVIRUS
(FR) VACCIN AMELIORANT L'IMMUNITE PROTECTRICE VIS-A-VIS DU VIRUS DE L'HEPATITE C AU MOYEN D'ADN PLASMIDIQUE ET D'ADENOVIRUS RECOMBINANT
Abstract: front page image
(EN)The present invention relates to a vaccine enhancing the protective immunity to Hepatitis C virus using plasmid DNA recombinant adenovirus, more particularly to a vaccine consisting of &Dgr; core-E1-E2 expressing DNA vaccine, nonstructural protein NS3 and NS4 expressing DNA vaccine, nonstructural protein NS5 expressing DNA vaccine and recombinant adenovirus vaccine, and method for administration of the vaccine by priming with the DNA vaccines described above and boosting with the recombinant adenovirus vaccine thereby enhancing the protective immunity to Hepatitis C virus.
(FR)La présente invention concerne un vaccin permettant d'améliorer l'immunité protectrice vis-à-vis du virus de l'hépatite C, au moyen d'ADN plasmidique et d'un adénovirus recombinant, plus spécifiquement, un vaccin comprenant un vaccin à ADN d'expression $g(D) core E1-E2, un vaccin à ADN d'expression de protéines NS3 et NS4, un vaccin à AND d'expression de protéines non structurelles NS5 et un vaccin associé à l'adénovirus recombinant. Cette invention a aussi trait à une méthode d'administration du vaccin par réalisation d'une première immunisation avec les vaccins à AND susmentionnés et par stimulation au moyen du vaccin associé à l'adénovirus recombinant, ce qui permet d'augmenter l'immunité protectrice vis-à-vis du virus de l'hépatite C.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: Korean (KO)