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Machine translation
1. (WO2004026908) Wnt MEDIATED ErbB SIGNALLING, COMPOSITIONS AND USES RELATED THERETO
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/026908    International Application No.:    PCT/EP2003/010469
Publication Date: 01.04.2004 International Filing Date: 19.09.2003
Chapter 2 Demand Filed:    27.03.2004    
IPC:
C07K 16/28 (2006.01), C07K 16/32 (2006.01), G01N 33/50 (2006.01), G01N 33/574 (2006.01), G01N 33/74 (2006.01)
Applicants: NOVARTIS FORSCHUNGSSTIFTUNG, ZWEIGNIEDERLASSUNG FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH [CH/CH]; Maulbeerstrasse 66, CH-4058 Basel (CH) (For All Designated States Except US).
CIVENNI, Gianluca [IT/CH]; (CH) (For US Only).
HOLBRO, Thomas [CH/CH]; (CH) (For US Only).
HYNES, Nancy [US/CH]; (CH) (For US Only)
Inventors: CIVENNI, Gianluca; (CH).
HOLBRO, Thomas; (CH).
HYNES, Nancy; (CH)
Common
Representative:
NOVARTIS FORSCHUNGSSTIFTUNG, ZWEIGNIEDERLASSUNG FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH; Maulbeerstrasse 66, CH-4058 Basel (CH)
Priority Data:
0221952.5 20.09.2002 GB
Title (EN) Wnt MEDIATED ErbB SIGNALLING, COMPOSITIONS AND USES RELATED THERETO
(FR) SIGNALISATION ERBB INDUITE PAR WNT, COMPOSITIONS ET APPLICATIONS ASSOCIEES
Abstract: front page image
(EN)The present invention makes availables assays and reagents inhibiting ErbB signals produced by Wnt protein comprising contacting a cell expressing ErbB and Wnt receptor (Frizzled) with a Wnt antagonist in a sufficient amount to reduce the sensitivity of the cell to ErbB signalling.
(FR)La présente invention concerne des essais et des réactifs inhibant les signaux ErbB produits par la protéine Wnt, ces essais consistant à mettre une cellule exprimant ErbB et le récepteur Wnt (Frizzled) en contact avec un antagoniste à Wnt en quantité suffisante pour réduire la sensibilité de la cellule à la signalisation ErbB.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)