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1. (WO2004026877) IMIDAZOPYRAZINES AS CYCLIN DEPENDENT KINASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/026877    International Application No.:    PCT/US2003/029209
Publication Date: 01.04.2004 International Filing Date: 19.09.2003
Chapter 2 Demand Filed:    24.03.2004    
IPC:
C07D 487/04 (2006.01)
Applicants: SCHERING CORPORATION [US/US]; 2000 Galloping Hill Road, Kenilworth, NJ 07033-0530 (US)
Inventors: PARUCH, Kamil; (US).
GUZI, Timothy, J.; (US).
DWYER, Michael, P.; (US).
DOLL, Ronald, J.; (US).
GIRIJAVALLABHAN, Viyyoor, M.; (US).
MALLAMS, Alan, K.; (US)
Agent: KALYANARAMAN, Palaiyur, S.; Schering-Plough Corporation, Patent Department - K-6-1 1990, 2000 Galloping Hill Road, Kenilworth, NJ 07033-0530 (US)
Priority Data:
60/412,997 23.09.2002 US
Title (EN) IMIDAZOPYRAZINES AS CYCLIN DEPENDENT KINASE INHIBITORS
(FR) IMIDAZOPYRAZINES UTILISES EN TANT QU'INHIBITEURS DE KINASE DEPENDANT DE LA CYCLINE
Abstract: front page image
(EN)In its many embodiments, the present invention provides a novel class of imidazo[1,2-a]pyrazine compounds of formula (III) as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
(FR)Dans plusieurs modes de réalisation de l'invention, on utilise une nouvelle classe de composés imidazo[1,2-a]pyrazine de formule (III) en tant qu'inhibiteurs de kinases dépendant de la cycline. L'invention concerne également des procédés de préparation desdits composés, des compositions pharmaceutiques contenant un ou plusieurs composés, des procédés de préparation de formulations pharmaceutiques comprenant un ou plusieurs composés, et des méthodes de traitement, de prévention, d'inhibition ou d'amélioration d'une ou plusieurs maladies associées aux CDK au moyen des composés ou des compositions pharmaceutiques de l'invention.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, HR, HU, ID, IL, IN, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LU, LV, MA, MD, MG, MK, MN, MX, MZ, NI, NO, NZ, PG, PH, PL, PT, RO, RU, SC, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UZ, VC, VN, YU, ZA, ZM.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)