Search International and National Patent Collections

1. (WO2004026848) OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPERATION AND THEIR USE AS ANTIMYCOBACTERIAL AGENTS

Pub. No.:    WO/2004/026848    International Application No.:    PCT/IN2002/000190
Publication Date: Apr 1, 2004 International Filing Date: Sep 20, 2002
IPC: C07D 263/20
C07D 413/10
C07D 413/14
Applicants: LUPIN LIMITED
ARORA, Sudershan, Kumar
PATIL, Vijaykumar, Jagdishwar
NAIR, Prathap, Sreedharan
DIXIT, Prasad, Purushottam
AJAY, Shankar
SINHA, Rakesh, Kumar
Inventors: ARORA, Sudershan, Kumar
PATIL, Vijaykumar, Jagdishwar
NAIR, Prathap, Sreedharan
DIXIT, Prasad, Purushottam
AJAY, Shankar
SINHA, Rakesh, Kumar
Title: OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPERATION AND THEIR USE AS ANTIMYCOBACTERIAL AGENTS
Abstract:
Novel compounds belonging to the class of oxazolidinones possessing potent antimycobacterial properties especially useful in the treatment of acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium-intracellular complex, M. fortuitum and M. kansai. The compound and its pharmaceutically acceptable salts thereof act as antibacterial agents. Also disclosed is a method for inhibiting growth of mycobacterial cells a well as a method of treating mycobacterial conditions such as Mycobacterium tuberculoses, drug resistant Mycobacterium tuberculosis, Mycobacterium avium-intracellular complex, M. fortuitum and M. kansai, comprising administering an antimycobacterially effective amount of the said compound and/or pharmaceutically acceptable salts thereof. There is also disclosed a process for the manufacture of the said compound or its pharmaceutically acceptable salts.