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1. (WO2004026837) HISTAMINE H3 RECEPTOR ANTAGONISTS, PREPARATON AND THERAPEUTIC USES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/026837    International Application No.:    PCT/US2003/025860
Publication Date: 01.04.2004 International Filing Date: 12.09.2003
Chapter 2 Demand Filed:    03.03.2004    
IPC:
C07D 209/04 (2006.01), C07D 209/22 (2006.01), C07D 209/24 (2006.01), C07D 209/26 (2006.01), C07D 215/06 (2006.01), C07D 215/08 (2006.01), C07D 215/20 (2006.01), C07D 215/227 (2006.01)
Applicants: ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center, Indianapolis, IN 46285 (US) (For All Designated States Except US).
BEAVERS, Lisa, Selsam [US/US]; (US) (For US Only).
FINLEY, Don, Richard [US/US]; (US) (For US Only).
GADSKI, Robert, Alan [US/US]; (US) (For US Only).
HIPSKIND, Philip, Arthur [US/US]; (US) (For US Only).
JESUDASON, Cynthia, Darshini [US/US]; (US) (For US Only).
PICKARD, Richard, Todd [US/US]; (US) (For US Only).
STEVENS, Freddie, Craig [US/US]; (US) (For US Only).
SEIDAM, Christopher, Stephen [US/US]; (US) (For US Only)
Inventors: BEAVERS, Lisa, Selsam; (US).
FINLEY, Don, Richard; (US).
GADSKI, Robert, Alan; (US).
HIPSKIND, Philip, Arthur; (US).
JESUDASON, Cynthia, Darshini; (US).
PICKARD, Richard, Todd; (US).
STEVENS, Freddie, Craig; (US).
SEIDAM, Christopher, Stephen; (US)
Agent: WOOD, Dan, L.; Eli Lilly and Company, P.O. Box 6288, Indianapolis, IN 46206-6288 (US).
BURNSIDE, Ivan, J.; Eli Lilly and Company, P.O. Box 6288, Indianapolis, IN 46206-6288 (US)
Priority Data:
60/411,625 18.09.2002 US
Title (EN) HISTAMINE H3 RECEPTOR ANTAGONISTS, PREPARATON AND THERAPEUTIC USES
(FR) ANTAGONISTES DU RECEPTEUR H3 D'HISTAMINE, PREPARATION ET APPLICATIONS THERAPEUTIQUES
Abstract: front page image
(EN)The present invention discloses novel compounds of Formula ( I ) or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I), as well as methods of using them to treat obesity and other histamine H3 receptor-related diseases.
(FR)La présente invention a trait à de nouveaux composés de formule (I) ou leurs sels pharmaceutiquement acceptables qui présentent une activité antagoniste du récepteur H3 d'histamine ainsi qu'à des procédés de préparations de tels composés. Dans un autre mode de réalisation, l'invention a trait à des compositions pharmaceutiques comprenant des composés de formule (I), ainsi que des procédés de leur utilisations pour le traitement de l'obésité et d'autres maladies associées au récepteur H3 d'histamine.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)