WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2004026828) PYRROLE DERIVATIVES AS ANTIMYCOBACTERIAL COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/026828    International Application No.:    PCT/IN2002/000189
Publication Date: 01.04.2004 International Filing Date: 20.09.2002
Chapter 2 Demand Filed:    02.02.2004    
IPC:
C07D 207/335 (2006.01), C07D 401/04 (2006.01), C07D 401/12 (2006.01), C07D 401/14 (2006.01), C07D 403/04 (2006.01), C07D 403/12 (2006.01), C07D 405/12 (2006.01), C07D 405/14 (2006.01), C07D 417/06 (2006.01)
Applicants: LUPIN LIMITED [IN/IN]; 159, C.S.T. Road, Kalina, Santacruz (East), Mumbai 400 098, Maharashtra (IN) (For All Designated States Except US).
ARORA, Sudershan, Kumar [US/IN]; (IN) (For US Only).
SINHA, Neelima [IN/IN]; (IN) (For US Only).
JAIN, Sanjay [IN/IN]; (IN) (For US Only).
UPADHAYAYA, Ram, Shankar [IN/IN]; (IN) (For US Only).
JANA, Gourhari [IN/IN]; (IN) (For US Only).
AJAY, Shankar [IN/IN]; (IN) (For US Only).
SINHA, Rakesh, Kumar [IN/IN]; (IN) (For US Only)
Inventors: ARORA, Sudershan, Kumar; (IN).
SINHA, Neelima; (IN).
JAIN, Sanjay; (IN).
UPADHAYAYA, Ram, Shankar; (IN).
JANA, Gourhari; (IN).
AJAY, Shankar; (IN).
SINHA, Rakesh, Kumar; (IN)
Agent: MAJUMDAR, S.; S. Majumdar & Co., 5, Harish Mukherjee Road, Calcutta 700 025 (IN)
Priority Data:
Title (EN) PYRROLE DERIVATIVES AS ANTIMYCOBACTERIAL COMPOUNDS
(FR) DERIVES DE PYRROLE SERVANT DE COMPOSES ANTI-MYCOBACTERIENS
Abstract: front page image
(EN)Novel pyrrole derivatives of formula (I), and their pharmaceutically acceptable acid addition salts having superior antimycobacterial activity against clinically sensitive as well as resistant strains of Mycobacterium tuberculosis as well as having lesser toxicity compared to known compounds. The use of the novel compounds of formula (I) for treatment of latent tuberculosis including Multi Drug Resistant Tuberculosis (MDR TB). The methods for preparation of the novel compounds, pharmaceutical compositions containing the novel compounds and method of treating MDR TB by administration of compounds of formula (I).
(FR)L'invention concerne de nouveaux dérivés de pyrrole de formule (I) et leurs sels d'addition acides pharmaceutiquement acceptables ayant une activité anti-mycobactérienne supérieure par rapport à une sensibilité clinique ainsi que des souches résistantes de bacille de Koch ainsi qu'une toxicité moindre par rapport aux composés connus. L'utilisation des nouveaux composés de formule (I) dans le traitement de la tuberculose latente, y compris la tuberculose multirésistante aux antibiotiques (MDR TB). Les procédés de préparation des nouveaux composés, des compositions pharmaceutiques contenant les nouveaux composés et une méthode de traitement de la MDR TB par l'administration de composés de formule (I) font également l'objet de cette invention.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)