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1. (WO2004026827) PYRROLIDONE DERIVATIVES AS MAOB INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/026827    International Application No.:    PCT/EP2003/010384
Publication Date: 01.04.2004 International Filing Date: 18.09.2003
Chapter 2 Demand Filed:    27.03.2004    
IPC:
C07D 207/273 (2006.01), C07D 207/277 (2006.01)
Applicants: F. HOFFMANN-LA ROCHE AG [CH/CH]; 124, Grenzacherstrasse, CH-4070 Basle (CH)
Inventors: IDING, Hans; (DE).
JOLIDON, Synese; (CH).
KRUMMENACHER, Daniela; (CH).
RODRIGUEZ SARMIENTO, Rosa, Maria; (CH).
THOMAS, Andrew, William; (CH).
WIRZ, Beat; (CH).
WOSTL, Wolfgang; (DE).
WYLER, Rene; (CH)
Agent: BRAUN, Axel; 124 Grenzacherstrasse, CH-4070 Basle (CH)
Priority Data:
02021319.5 20.09.2002 EP
Title (EN) PYRROLIDONE DERIVATIVES AS MAOB INHIBITORS
(FR) DERIVES DE PYRROLIDONE UTILISES COMME INHIBITEURS DE LA MAOB
Abstract: front page image
(EN)Racemic enantiomerically pure 4- pyrrolidino derivatives of formula (I), processes for their preparation, pharmaceutical compositions comprising said derivatives, and their use in the prevention and treatment of illness, in particular which is mediated by monoamine oxidase B inhibitors, in particular Alzheimer’s disease or senile dementia.
(FR)L'invention concerne des dérivés racémiques 4-pyrrolidino énantiomériquement purs de la formule (I), leurs procédés de préparation, des compositions pharmaceutiques comprenant ces dérivés et leur utilisation dans la prévention et le traitement de maladies, en particulier de maladies induites par les inhibiteurs de la monoamine-oxydase de type B, et plus précisément de la maladie d'Alzheimer ou de la démence sénile.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)