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1. (WO2004026826) 4-PYRROLIDINO-PHENYL-BENZYL ETHER DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2004/026826    International Application No.:    PCT/EP2003/010383
Publication Date: 01.04.2004 International Filing Date: 18.09.2003
Chapter 2 Demand Filed:    27.03.2004    
IPC:
C07D 207/273 (2006.01), C07D 207/277 (2006.01)
Applicants: F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124, CH-4070 Basel (CH)
Inventors: JOLIDON, Synese; (CH).
RODRIGUEZ-SARMIENTO, Rosa, Maria; (CH).
THOMAS, Andrew, William; (CH).
WOSTL, Wolfgang; (DE).
WYLER, Rene; (CH)
Agent: BRAUN, Axel; Grenzacherstrasse 124, CH-4070 Basel (CH)
Priority Data:
02021319.5 20.09.2002 EP
Title (EN) 4-PYRROLIDINO-PHENYL-BENZYL ETHER DERIVATIVES
(FR) DERIVES DE 4-PYRROLIDINO-PHENYL-BENZYL ETHER
Abstract: front page image
(EN)Racemic or enantiomerically pure 4-pyrrolidino derivatives of formula (I), processes for their preparation, pharmaceutical compositions comprising said derivatives, and their use in the prevention and treatment of illness, e.g. which are mediated by monoamine oxidase B inhibitors, in particular Alzheimer's disease or senile dementia.
(FR)L'invention concerne des dérivés racémiques ou énantiomériquement purs 4-pyrrolidino de la formule (I), leurs procédés de préparation, des compositions pharmaceutiques comprenant ces dérivés et leur utilisation dans la prévention et le traitement de maladies, en particulier de maladies induites par les inhibiteurs de la monoamine-oxydase de type B, et plus précisément de la maladie d'Alzheimer ou de la démence sénile.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)