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1. (WO2004026279) EFFERVESCENT FORMULATIONS OF OXYTOCIN

Pub. No.:    WO/2004/026279    International Application No.:    PCT/GB2003/004146
Publication Date: Apr 1, 2004 International Filing Date: Sep 19, 2003
IPC: A61K 9/00
A61K 9/16
A61K 9/20
A61K 9/46
A61K 38/11
Applicants: ARDANA BIOSCIENCE LIMITED
LARSEN, Finn
Inventors: LARSEN, Finn
Title: EFFERVESCENT FORMULATIONS OF OXYTOCIN
Abstract:
An effervescent formulation comprising oxytocin, preferably comprising multilayer effervescent microspheres containing an acidic substance, a basic substance and water-soluble isolating agent. An effervescent formulation comprising oxytocin wherein dissolution in water of the multilayer effervescent microspheres leads, after almost immediate effervescence, to a solution or a homogeneous dispersion of the oxytocin. The formulation is used for the induction or augmentation of labour or treatment or prevention of postpartum haemorrhage or treatment of missed abortion or facilitation of lactation.